This is a case report of a patient with schizophrenic disorder, followed up prospectively over a period of six years through four episodes of illness. Her experience of a focal physical symptom as a consistent prodromal feature of each relapse forms the focus of the report as such a clinical phenomenon has not been recorded before. The possible reason for such presentation and the value of identifying the prodromal symptoms in the control of relapse are discussed.
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J Behav Ther Exp Psychiatry
March 2025
Harvard Medical School, Cambridge, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, USA. Electronic address:
Rep Prog Phys
December 2024
School of Electrical Engineering-Physical Electronics, Center of Light-Matter Interaction, Tel Aviv University, Ramat Aviv 69978, Israel.
It has been shown that the spontaneous emission rate of photons by free electrons, unlike stimulated emission, is independent of the shape or modulation of the quantum electron wavefunction (QEW). Nevertheless, here we show that the quantum state of the emitted photons is non-classical and does depend on the QEW shape. This non-classicality originates from the shape dependent off-diagonal terms of the photon density matrix.
View Article and Find Full Text PDFPsychiatry Res
December 2024
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
The impact of childhood abuse on the presentation of bipolar disorder could be further elucidated by comparing the networks of affective symptoms among individuals with and with no history of childhood abuse. Data from 476 participants in the Clinical Health Outcomes Initiative in Comparative Effectiveness for Bipolar Disorder study were used to fit several regularised Gaussian Graphical Models. Differences in the presentation of depressive and manic symptoms were uncovered: only among participants with a history of childhood abuse, inadequacy and pessimism were central symptoms in the network of depressive symptoms, while racing thoughts was an important symptom in the network of manic symptoms.
View Article and Find Full Text PDFInt J Psychophysiol
November 2024
Anxiety Disorders Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA; Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
Individuals with hoarding disorder (HD) have difficulty parting with personal possessions, which leads to the accumulation of excessive clutter. According to a proposed biphasic neurobiological model, HD is characterized by blunted central and peripheral nervous system activity at rest and during neutral (non-discarding) decisions, and exaggerated activity during decision-making about discarding personal possessions. Here, we compared the error-related negativity (ERN) and psychophysiological responses (skin conductance, heart rate and heart rate variability, and end tidal CO) during neutral and discarding-related decisions in 26 individuals with HD, 37 control participants with anxiety disorders, and 28 healthy control participants without psychiatric diagnoses.
View Article and Find Full Text PDFJMIR Res Protoc
July 2024
Department of Psychology and Center for Children and Families, Florida International University, Miami, FL, United States.
Background: Adolescence is marked by an increasing risk of depression and is an optimal window for prevention and early intervention. Personalizing interventions may be one way to maximize therapeutic benefit, especially given the marked heterogeneity in depressive presentations. However, empirical evidence that can guide personalized intervention for youth is lacking.
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