Objectives: To evaluate the epidemiological aspects of adenoid cystic carcinoma (ACC) and to evaluate the different therapeutic possibilities as well as the percentage of survival.
Study Design: A retrospective, meta-analytic, observational study was carried out by selecting a total of 13 articles, which provided a sample size of 263 cases of patients who had been diagnosed with ACC in the minor salivary glands.
Results: ACC was found to be more common among women (56.5%) and the average age at diagnosis was 55.26 years old. The primary location of the tumor was in the palate in 57% of the cases, the predominant pattern being cribiform. The treatment of choice was therapy combined with surgery and radiotherapy in 62.7% of the subjects. The overall survival rate was 70.76% and 56.76%, at 5 and 10 years respectively.
Conclusions: Early detection of adenoid cystic carcinoma is necessary in order to enable making an earlier prognosis and thus enable a better quality of life for the patient.
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http://dx.doi.org/10.4317/medoral.17200 | DOI Listing |
Cureus
November 2024
Radiation Oncology, Faculty of Medicine and Pharmacy - Mohammed First University, oujda, MAR.
Adenoid cystic carcinoma (ACC) of the submandibular gland is a rare and highly aggressive malignancy, distinguished by its tendency for perineural invasion and distant metastasis, particularly to the lungs and bones. The management of ACC is challenging due to its biological variability and the absence of specific randomized controlled trials to guide treatment. This report aims to encapsulate the clinical features, histological profile, diagnostic workup, and management options for submandibular gland ACC, with an emphasis on recent advancements in understanding and treatment.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
Adenoid cystic carcinoma is a malignant tumor of the head and neck, this article reports a case of a large adenoid cystic carcinoma of the skull base, with the lesion involving the sphenoid sinus, sphenoid bone wings, pterygopalatine fossa, nfratemporal fossa, hard palate, and other structures. The treatment plan consisted of surgical excision, primary reconstrction of the surgical defect,and postoperative radiotherapy, resulting in a favorable prognosis for the patient.
View Article and Find Full Text PDFGeorgian Med News
October 2024
1Onkoderma - Clinic for Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.
Cutaneous cylindromas are rare, slow-growing adnexal tumors commonly found on the capillitium or face. When located on the capillitium, they can cluster together, forming a headgear-like structure that gives the characteristic "turban" appearance. Brooke-Spiegler syndrome, an autosomal dominant condition, is typically benign, though malignant transformation can occur.
View Article and Find Full Text PDFDiagn Cytopathol
December 2024
Department of Pathology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Introduction: Thyroid lesions are one of the most common diseases observed in clinical practice in the North India. These diseases have distinct cytological morphology and thus FNAC is done frequently. Here we report a case of adenomatoid goitre mimicking adenoid cystic carcinoma (ACC) of salivary gland on cytology.
View Article and Find Full Text PDFJ Int Med Res
December 2024
Department of Pathology, Chungbuk National University Hospital, Cheongju, Korea.
Adenoid cystic carcinoma (ACC) rarely occurs in the nasolacrimal duct (NLD), and when it does, it has nonspecific manifestations. To the best of our knowledge, one case of ACC in the NLD has been reported in the literature. Herein, we report a second case of ACC in the left NLD, concerning a man in his late 60s.
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