Purpose: The aim of this study was to compare characteristics of rectal compression and stapled anastomoses at multiple time points.
Methods: A total of 50 domestic pigs underwent a rectal anastomosis with a compression device or a circular stapler. They were sacrificed at zero-time, 2 days, 1 week, 1 month, and 3 months. Burst and maximal tolerated pressure and sites of failure, internal diameters, and radiographic leak rates were assessed. Desmosine (elastin) levels were determined.
Results: There were no clinical or radiographic leaks. Overall, 10 out of 27 (37%) compression anastomoses burst at higher pressures than the 14 out of 24 (58%) stapled anastomoses. Mean circumference and anastomotic index were greater for the EndoCAR at 1 week and 3 months. Desmosine levels were similar.
Conclusions: In the porcine model, compression rectal anastomoses with the EndoCAR had improved bursting pressures and internal circumference compared with circular stapled anastomoses.
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