Comparison between spontaneous sedimentation method and Paratest® for the diagnosis of intestinal parasitic infections.

Trans R Soc Trop Med Hyg

Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610.000, Porto Alegre, RS, Brazil.

Published: October 2011

Correct diagnosis of parasitic infections is essential for the treatment of individuals avoiding indiscriminate use of anthelmintics which increases drug resistance. In a comparative study between the spontaneous sedimentation technique and Paratest(®), 140 stool samples were analyzed for the detection of parasites. The prevalence was 12.7% obtained by the spontaneous sedimentation method but only 5.7% using Paratest(®). Paratest(®) has shown a high proportion of false-negative results, lower sensitivity and negative predictive values compared with the spontaneous sedimentation method. Further optimization and studies of the Paratest(®) method are necessary for wider use in clinical diagnosis.

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http://dx.doi.org/10.1016/j.trstmh.2011.06.002DOI Listing

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