Unlabelled: The aim of the study was to evaluate clinical and laboratory findings and predisposing factors for Listeria monocytogenes (Lm) meningitis.
Methods: 17 intensive care unit patients (12 M, 5 F), aged 54.4 +/- 15.3 yrs, were studied. CNS listeriosis was confirmed by culture of cerebrospinal fluid (CSF) or CSF pleocytosis coupled with Lm bacteriemia.
Results: The frequency of central nervous system (CNS) listeriosis among patients with bacterial meningitis was 5.5%. Meningeal signs were present in all patients. 15 patients had impaired level of consciousness. Possible predisposing factors occurred in 15 patients. The average CSF white blood cell count was 1034 +/- 1064 cells/microl.
Conclusion: Symptoms and signs of patients with CNS listeriosis were not different from those usually found in other bacterial meningitis. A trend toward fewer WBC in CSF was revealed. Most patients with Lm meningitis were immunocompromised.
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