[Experimental quality assessment of APTT-control reagent kits in the study of heparin-containing plasma in therapeutic ranges].

Investigation of activated partial thromboplastin time (APTT) in the plasma samples containing different levels of heparin determines the following parameters of the quality of APTT-control reagent kits: coefficient of variation, linearity, sensitivity, and detection. The kit is shown to meet GOST P 51352-99 requirements. The determination of the validity coefficient of approximation has proven a directly proportional functional relationship of the APTT values to the level of heparin in therapeutic ranges in the logarithmic coordinate system. The kit may be used to monitor heparin therapy.