A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Synthesis of a cyclic peptide/protein using the NEXT-A reaction followed by cyclization. | LitMetric
Browse Categories

Synthesis of a cyclic peptide/protein using the NEXT-A reaction followed by cyclization.

Toshimasa Hamamoto Masahiko Sisido Takashi Ohtsuki Masumi Taki

Chem Commun (Camb)

Department of Medical and Bioengineering Science, Chemical Biology Area, Division of Chemistry and Biochemistry, Okayama University, 1-1-1, Tsushimanaka, Okayama, 700-0082, Japan.

Published: August 2011

By using the NEXT-A reaction, we introduced a non-natural amino acid at the N-terminus of a peptide/protein that contained a cysteine unit. The side chain of the introduced amino acid spontaneously reacted with the cysteine to afford a cyclic peptide/protein.

Download full-text PDF

 Source
http://dx.doi.org/10.1039/c1cc12196kDOI Listing

Publication Analysis

Top Keywords

cyclic peptide/protein
8
next-a reaction
8
amino acid
8
synthesis cyclic
4
peptide/protein next-a
4
reaction cyclization
4
cyclization next-a
4
reaction introduced
4
introduced non-natural
4
non-natural amino
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

Privacy Policy Site Map

© LitMetric 2025. All rights reserved.