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<PubmedArticle><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21733954</PMID><DateCompleted><Year>2012</Year><Month>05</Month><Day>22</Day></DateCompleted><DateRevised><Year>2022</Year><Month>04</Month><Day>08</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1940-1574</ISSN><JournalIssue CitedMedium="Internet"><Volume>63</Volume><Issue>3</Issue><PubDate><Year>2012</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Angiology</Title><ISOAbbreviation>Angiology</ISOAbbreviation></Journal><ArticleTitle>Hematologic parameters and angiographic progression of coronary atherosclerosis.</ArticleTitle><Pagination><StartPage>213</StartPage><EndPage>217</EndPage><MedlinePgn>213-7</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1177/0003319711412763</ELocationID><Abstract><AbstractText>Hematologic parameters have prognostic importance in cardiovascular disease. However, the relation between atherosclerosis progression and hematologic parameters is not well defined. A total of 394 patients requiring repeat coronary angiography were included in the study. According to angiography, patients were divided into 2 groups, progressive (n = 196) and nonprogressive (n = 198) diseases. Hematologic parameters including mean platelet volume (MPV) and neutrophil/lymphocyte (N/L) ratio were measured. Glucose, creatinine, and cholesterol were significantly higher in the progressive group. Mean platelet volume count was similar in both groups. The N/L ratio was significantly higher in the progressive group (5.0 &#xb1; 5.1 vs 3.2 &#xb1; 3; P = .001). In multivariate analysis, the N/L ratio was significantly related with progression (relative risk [RR]: 2.267, 95% CI: 1.068-4.815, P = .03). Progression rate was significantly high in patients with high N/L ratio (39% vs 56%). Our results suggest that the N/L ratio is a predictor of progression of atherosclerosis.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kalay</LastName><ForeName>Nihat</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey. nihatkalay@hotmail.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dogdu</LastName><ForeName>Orhan</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Koc</LastName><ForeName>Fatih</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Yarlioglues</LastName><ForeName>Mikail</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Ardic</LastName><ForeName>Idris</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Akpek</LastName><ForeName>Mahmut</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Cicek</LastName><ForeName>Davran</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Oguzhan</LastName><ForeName>Abdurrahman</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Ergin</LastName><ForeName>Ali</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Kaya</LastName><ForeName>Mehmet G</ForeName><Initials>MG</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>07</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Angiology</MedlineTA><NlmUniqueID>0203706</NlmUniqueID><ISSNLinking>0003-3197</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006454">Hemoglobins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001772" MajorTopicYN="N">Blood Cell Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017023" MajorTopicYN="N">Coronary Angiography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003324" MajorTopicYN="N">Coronary Artery Disease</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018450" MajorTopicYN="N">Disease Progression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004909" MajorTopicYN="N">Erythrocyte Indices</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006454" MajorTopicYN="N">Hemoglobins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>7</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>7</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">21733954</ArticleId><ArticleId IdType="doi">10.1177/0003319711412763</ArticleId><ArticleId IdType="pii">0003319711412763</ArticleId></ArticleIdList></PubmedData></PubmedArticle></PubmedArticleSet>