Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1556/OH.2011.29171 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Utility of Circulating Tumor DNA Assay in Identifying Mutations and Guiding Matched Targeted Therapy in Lung Cancers.
Clin Med Insights Oncol
October 2024
Department of Bioinformatics, Beijing USCI Medical Devices Co., Ltd., Beijing, China.
Background: Tumor genomic profiling has a significant impact on the selection of targeted therapy. Circulating tumor DNA (ctDNA) has emerged as a noninvasive, and reproducible assay compared with tissue biopsy. We aimed to evaluate its utility in identifying mutations and guiding targeted therapy for lung cancer.
View Article and Find Full Text PDFReductions of food intake and body weight in diet-induced obese rats following chronic treatment with a monomeric peptide multiagonist.
Clin Nutr
July 2024
Seattle Children's Research Institute, 1900 Ninth Ave, Seattle WA 98101, USA; Seattle Children's Hospital, University of Washington, Department of Pediatrics, Seattle, WA 98105, USA. Electronic address:
Introduction: While therapies based on endogenous gut peptides such as glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) have been compelling therapeutic agents for obesity and type 2 diabetes (T2D), only a few have achieved long-term weight loss and all have shown significant side-effects, including nausea/malaise and gastrointestinal ailments.
Objective: As the pathophysiology of obesity is driven by dysregulation of multiple, inter-related, pathways, we tested a novel peptide targeting multiple receptors of complementary neurocircuits regulating the controls of energy balance.
Methods: Response to daily injections of GEP44, a GLP-1R and neuropeptide Y1R and Y2R receptor (Y1R/Y2R) triple agonist was tested vs.
In Vitro Antifungal Activity of Selected Essential Oils against Drug-Resistant Clinical spp. Strains.
Molecules
October 2023
Department Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.
Background: Treatment options for aspergillosis include amphotericin B (AMB) and azole compounds, such as itraconazole (ITZ). However, serious side effects related to these antifungal agents are increasingly evident, and resistance continues to increase. Currently, a new trend in drug discovery to overcome this problem is represented by natural products from plants, or their extracts.
View Article and Find Full Text PDF[Efectividad de las terapias no farmacológicas en personas con alzheimer: una revisión sistemática.].
Rev Esp Salud Publica
October 2023
Escuela de Enfermería La Fe; Centro adscrito a la Universidad de Valencia. Grupo de Investigación Arte y Ciencia del Cuidado (GREIACC); Instituto de Investigación Sanitaria La Fe (IIS La FE). Valencia. España.
Objective: Alzheimer's disease has become the great epidemic of the 21st century, being a challenge for the sustainability of the social and health system. Alzheimer's causes disability and dependency among the elderly, requiring continued care with therapies that improve the health and quality of life of these people. The objective of this paper was to evaluate the effectiveness of non-pharmacological therapies applied to people with Alzheimer's in Primary Care.
View Article and Find Full Text PDFModified study designs to expand treatment options in personalised oncology: a multistakeholder view.
Eur J Cancer
November 2023
Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany. Electronic address:
Personalised oncology, whereby patients are given therapies based on their molecular tumour profile, is rapidly becoming an essential part of optimal clinical care, at least partly facilitated by recent advances in next-generation sequencing-based technology using liquid- and tissue-based biopsies. Consequently, clinical trials have shifted in approach, from traditional studies evaluating cytotoxic chemotherapy in largely histology-based populations to modified, biomarker-driven studies (e.g.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!