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UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer.
J Transl Med
January 2025
Department of Gynecology, The Fourth Hospital of Hebei Medical University, No.12 Jiankang Road, Shijiazhuang, 050000, Hebei, China.
Background: Immune cells within tumor tissues play important roles in remodeling the tumor microenvironment, thus affecting tumor progression and the therapeutic response. The current study was designed to identify key markers of plasma cells and explore their role in high-grade serous ovarian cancer (HGSOC).
Methods: We utilized single-cell sequencing data from the Gene Expression Omnibus (GEO) database to identify key immune cell types within HGSOC tissues and to extract related markers via the Seurat package.
A new approach for evaluating maize transgressive segregants and their three-way cross potential in the S4 convergent breeding population.
BMC Plant Biol
January 2025
Plant Production Department, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
The development of transgressive segregant (TS) selection on convergent breeding populations of S4 maize is a concept that is rarely applied. However, the development of TS is necessary to accelerate maize breeding pipelines. Therefore, the objectives of this study were (1) to develop the concept of TS selection and (2) to select S4 TS maize to be developed as hybrid cross parents.
View Article and Find Full Text PDFBiomechanical analysis of a newly designed and 3D printed plate-locking interbody cage: an observational study of finite element analysis.
Sci Rep
January 2025
Department of Orthopaedic Trauma, The Second Affiliated Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian, 116027, Liaoning, China.
Anterior cervical interbody fusion (ACDF) has become a classic surgical procedure for the treatment of cervical degenerative diseases, and various interbody cages are widely used in this procedure. We used 3D printing technology to produce a new type of plate-locking cage, anticipating to achieve high fusion rate with the high biomechanical stability. This study is to compare the biomechanical characteristics between a newly designed interbody cage and a conventional Zero-profile cage during ACDF using finite element analysis.
View Article and Find Full Text PDFNano urea's environmental edge and economic efficacy in boosting wheat grain yield across diverse Indian agro-climates.
Sci Rep
January 2025
ICAR-Indian Institute of Millets Research, Rajendranagar, Hyderabad, 500 030, Telangana, India.
The gradual increase in the consumption of mineral nitrogen is leading to heightened levels of harmful air pollutants, particularly NO emissions from the agriculture sector. A potential solution to address the issues arising from the excessive use of urea in wheat is the substitution of conventional urea with nano urea. This study aimed to quantify the effects of nano urea, both independently and in conjunction with prilled urea, under various agroclimatic and sowing conditions in India.
View Article and Find Full Text PDFTrace elements increase replicability of microbial growth.
Open Biol
January 2025
Institute for Biological Physics, University of Cologne, Zülpicher Straße 77, Köln 50937, Germany.
Trace elements are often omitted from chemically defined growth media. From established properties of trace elements, we deduce that this omission makes experiments unnecessarily sensitive to unavoidable contamination with trace elements. We confirm this experimentally by growing 11 bacterial strains in high replicate with and without supplementing trace elements, keeping all other conditions as fixed as possible to isolate the effect of trace elements.
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