Acromegaly associated with a symptomatic Rathke's cyst.

Indian J Endocrinol Metab

Department of Endocrinology, Jaslok Hospital and Research Centre, Mumbai, India.

Published: April 2011

Our aim is to describe a case of acromegaly that was associated with symptomatic Rathke's cyst. We describe a young male student without any significant family history who presented with clinical and biochemical features consistent with growth hormone excess, which was confirmed with dynamic testing. He also described a persistent headache predating symptoms of growth hormone excess by 4 years. Magnetic resonance imaging (MRI) of the pituitary showed a large sellar mass which was thought to be a somatotroph adenoma. Trans-sphenoidal surgery was performed; however, a colloid lesion was identified by the neurosurgeon that proved to be a Rathke's cyst. The association of acromegaly with Rathke's cyst is very rare, with less than 10 cases found to be reported on review of literature. This is the first report from India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125006PMC
http://dx.doi.org/10.4103/2230-8210.81950DOI Listing

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