A young lady with swelling and stiffness of calf muscles.

Indian J Endocrinol Metab

Department of Medicine, JSS Medical College and Hospital, JSS University, Mysore, Karnataka, India.

Published: April 2011

AI Article Synopsis

  • Hypothyroidism can lead to various physical changes, including muscle-related issues.
  • Myopathy is a rare presentation of hypothyroidism, affecting muscle function.
  • Hoffman's syndrome is a specific type of hypothyroid myopathy characterized by weakness in proximal muscles and muscle pseudohypertrophy.

Article Abstract

Hypothyroidism causes a variety of changes in the body. Though uncommon, hypothyroidism can present as myopathy. Hoffman's syndrome is a specific, rare form of hypothyroid myopathy, which causes proximal weakness and pseudohypertrophy of muscles.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125002PMC
http://dx.doi.org/10.4103/2230-8210.81946DOI Listing

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