Glial heterotopia is a rare congenital mass lesion which often presents as a clinical surprise. We report a case of extranasal glial heterotopia in a neonate with unusual features. The presentation, management strategy, etiopathogenesis and histopathology of the mass lesion has been reviewed.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119938PMC
http://dx.doi.org/10.4103/0971-9261.78132DOI Listing

Publication Analysis

Top Keywords

glial heterotopia
12
clinical surprise
8
mass lesion
8
heterotopia maxilla
4
maxilla clinical
4
surprise glial
4
heterotopia rare
4
rare congenital
4
congenital mass
4
lesion presents
4

Similar Publications

() is a causative gene for genetic hydrocephalus found in hemorrhagic hydrocephalus () mice. The knockout (KO) rat has subcortical heterotopia with frequent brain hemorrhage as seen in mice. In this study, we report aberrant alpha-smooth muscle actin (α-SMA) expression in the wall of lateral ventricle of the KO rats.

View Article and Find Full Text PDF

Rare Pathology: Choristoma of the Palatine Tonsil in Otorhinolaryngology.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of ENT, Dr D Y Patil Medical college, Hospital and Research Centre, Dr D Y Patil Vidyapeeth, Pimpri, Pune, India.

Choristomas are aggregates of microscopically normal tissues in aberrant locations. They can be cartilage, bone, glial tissue, salivary gland, and thyroid tissue. Cartilaginous choristomas of the oral cavity are rare and occur most commonly on the tongue and less often in sites such as the soft palate and gingiva.

View Article and Find Full Text PDF

Subcortical heterotopia is a cortical malformation associated with epilepsy, intellectual disability, and an excessive number of cortical neurons in the white matter. Echinoderm microtubule-associated protein like 1 (EML1) mutations lead to subcortical heterotopia, associated with abnormal radial glia positioning in the cortical wall, prior to malformation onset. This perturbed distribution of proliferative cells is likely to be a critical event for heterotopia formation; however, the underlying mechanisms remain unexplained.

View Article and Find Full Text PDF

The uncommon, non-hereditary congenital abnormalities known as nasal glial heterotopias (NGH) are composed of heterotopic neuroglial tissue. Typically, NGH manifests in infancy, but occasionally it can also be seen in older children and adults. To rule out intracranial extension, magnetic resonance imaging (MRI) and computed tomography (CT) scans should be performed.

View Article and Find Full Text PDF
Article Synopsis
  • * A 3-year-old girl was found to have a cystic mass in her abdomen, leading to successful laparoscopic surgery, where the cysts contained various types of nerve and glial tissue.
  • * Most children with retroperitoneal neuroglial heterotopia are asymptomatic and may not show obvious signs; while complete surgical removal usually yields a good outcome, more research is needed to assess long-term results.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!