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Erdheim-Chester Disease is a rare systemic xanthogranulomatous infiltrating disease, characterized by lipid-laden histiocytes accumulating in various organs and almost always in bones. Etiology of the disease is still unknown. It may involve various organs and systems, such as musculoskeletal, cardiac, pulmonary, renal, gastrointestinal and central nervous system (CNS) as well as the skin.

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In the present case, a 66-year-old woman presented to the Specialty Hospital (Amman, Jordan) with recurrent post-menopausal bleeding. A pelvic ultrasound scan showed an abnormal endometrial thickness of 8 mm and no adnexal masses. An endometrial biopsy revealed abundant foamy histiocyte infiltration features suggestive of xanthogranulomatous endometritis.

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Xanthogranulomatous inflammation (XGI) is a rare, benign inflammatory condition of unclear pathogenesis, characterised by infiltration and subsequent destruction of normal tissue by lipid-laden macrophages together with lymphocytes and plasma cells. A 56-year-old gentleman was referred to the urology department of our hospital due to concerns that his right testicle felt firmer than his left over the preceding six months. He was investigated and subsequently underwent a right sided orchidectomy.

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Department of General and Minimal Invasive Surgery, Sher-I-Kashmir Institute of Medical Sciences Soura, Srinagar, Jammu and Kashmir, India.

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Introduction And Importance: Xanthogranulomatous inflammation of the female genital tract is a rare condition involving ovarian tubes characterized by chronic inflammation and destruction of pelvic organs, often mimicking pelvic malignancy.

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