First description of an Escherichia coli strain producing NDM-1 carbapenemase in Spain.

Antimicrob Agents Chemother

Department of Clinical Microbiology and Barcelona Centre for International Health Research (CRESIB), Hospital Clinic-IDIBAPS, University of Barcelona, Spain.

Published: September 2011

A carbapenem-resistant Escherichia coli strain (DVR22) was recovered from a stool specimen from a patient with traveler's diarrhea who had traveled to India. Molecular screening led to the first identification of NDM-1 in Spain. The bla(NDM-1) gene was located in a conjugative plasmid of ca. 300 kb that also contained the bla(CTX-M-15), bla(TEM-1), Δbla(DHA-1), and armA genes. In addition, bla(NDM-1) was preceded by an ISAba125 insertion element only found in Acinetobacter spp.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165357PMC
http://dx.doi.org/10.1128/AAC.00642-11DOI Listing

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