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Borna disease in an adult free-ranging Eurasian beaver (Castor fiber albicus).
J Comp Pathol
February 2024
Department of Veterinary Medicine, State Office for Consumer Protection of Sachsen-Anhalt, Stendal, Haferbreiter Weg 132-135, D-39576 Stendal, Germany.
Borna disease (BD) associated with a peracute bacterial septicaemia with Escherichia coli was diagnosed in an adult female, naturally infected, free-ranging Eurasian beaver of the subspecies Castor fiber albicus, clinically characterized by weight loss, depression, weakness and gurgled peristaltic sounds. The beaver was euthanized humanely. Necropsy and light microscopy revealed a non-purulent meningoencephalitis with typical mononuclear perivascular cuffs and parenchymal infiltrates.
View Article and Find Full Text PDFCase report: Fatal Borna virus encephalitis manifesting with basal brain and brainstem symptoms.
Front Neurol
January 2024
Department of Neurology and Neurointensive Care, Schoen Clinic Bad Aibling, Bad Aibling, Germany.
Background: Since the first report of fatal Borna virus-1 (BoDV-1) encephalitis in 2018, cases gradually increased. There is a lack of diagnostic algorithm, and there is no effective treatment so far.
Case Presentation: We report an acute BoDV-1 encephalitis in a 77-year-old female with flu-like onset, rapid progression to word-finding difficulties, personality changes, global disorientation, diffuse cognitive slowness, and gait ataxia and further deterioration with fever, meningism, severe hyponatremia, epileptic seizures, cognitive decline, and focal cortical and cerebellar symptoms/signs.
Acute and sub-acute ocular manifestations in pediatric patients with COVID-19: A systematic review.
Med Hypothesis Discov Innov Ophthalmol
April 2022
Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: The coronavirus disease 2019 (COVID-19) pandemic has been the most challenging health problem in the last 2 years. Post-COVID-19 multisystem inflammatory syndrome of children (MIS-C) is a severe post-COVID-19 complication in pediatric patients. Ocular manifestations may be the first presentation of MIS-C, wherein prompt treatment may improve outcomes.
View Article and Find Full Text PDFZika Virus Infection in Pregnant Women and Microcephaly.
Rev Bras Ginecol Obstet
May 2017
Universidade de São Paulo, São Paulo, SP, Brazil.
From the discovery of the Zika virus (ZIKV) in 1947 in Uganda (Africa), until its arrival in South America, it was not known that it would affect human reproductive life so severely. Today, damage to the central nervous system is known to be multiple, and microcephaly is considered the tip of the iceberg. Microcephaly actually represents the epilogue of this infection's devastating process on the central nervous system of embryos and fetuses.
View Article and Find Full Text PDFZika Virus Disease and Associated Neurologic Complications.
Curr Infect Dis Rep
January 2017
Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
Purpose Of Review: The purpose of this article is to review what is currently known about Zika virus (ZIKV) disease and associated neurologic complications.
Recent Findings: ZIKV is a mosquito-borne or sexually transmitted flavivirus rapidly spreading throughout the Americas. While ZIKV infection is usually asymptomatic, it may cause a non-specific illness with fever, rash, myalgia, headache, and/or non-purulent conjunctivitis.
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