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Benign phyllodes tumor of the distal end of the ureter: an extremely rare case and literature review.
BMC Urol
December 2024
Department of Pathology, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou City, Zhejiang Province, China.
A phyllodes tumor (PT) is a biphasic fibroepithelial lesion that is most commonly found in breast tissue, whereas it is uncommon in ureter tissue. Only one case has been documented so far. There are some similarities in histology and clinical characteristics between this type of tumor and PT of the female breast: the lesions can be surgically removed, but some recur locally and invade directly into the breast.
View Article and Find Full Text PDFGenomic Landscape of Malignant Phyllodes Tumors Identifies Subsets for Targeted Therapy.
JCO Precis Oncol
December 2024
Duke Cancer Institute, Duke University Hospital, Durham, NC.
Article Synopsis
- * A study analyzed 57 MPT samples using various genomic and immunohistochemical techniques, revealing low HER2 expression compared to common breast cancer, and identified frequent genetic alterations among different tumor sites.
- * The research emphasizes the potential of next-generation sequencing (NGS) to find actionable genetic changes, supporting its role in MPT treatment decisions and highlighting the need for further MPT molecular studies.
Breast tumor with giant borderline phyllodes: Case report and literature review.
Medicine (Baltimore)
November 2024
Department of Breast Surgery, The First Affiliated Hospital of Nanchang University, Jiangxi Province, China.
Rationale: Giant phyllodes tumors are rare fibroepithelial neoplasms, accounting for less than 1% of all primary breast tumors. Their main features are a single-round mass, progressive enlargement, and a high rate of local recurrence. A phyllodes tumor measuring more than 10 cm in diameter is usually defined as a "giant" tumor.
View Article and Find Full Text PDFDifferentiated Thyroid Cancers with Synchronous Second Primary Cancers: Case Series.
Indian J Otolaryngol Head Neck Surg
October 2024
The Gujarat Cancer and Research Institute, Ahmedabad, Gujarat India.
The incidence of synchronous second primary cancer (SSPC) with DIfferentiated Thyroid Cancers (DTC) is a very rare entity. Very few case reports and case series were published in the literature. To enumerate the clinicopathological data of patients with DTC with SSPC.
View Article and Find Full Text PDFCoexisting invasive ductal carcinoma arising within a benign phyllodes tumour.
BMJ Case Rep
October 2024
Medway NHS Foundation Trust, Gillingham, Medway, UK.
Article Synopsis
- A woman in her 40s with a 2-year history of a growing lump in her right breast was examined and found to have a significant mass, leading to MRI and biopsy evaluations.
- The diagnosis confirmed a benign phyllodes tumor, but also identified an incidental invasive ductal carcinoma and high-grade ductal carcinoma in situ within the excised tissue.
- After surgery and further treatments including radiotherapy and chemotherapy, the patient has remained disease-free for 20 months, highlighting the need for careful examination of phyllodes tumors to detect any malignant features.
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