Purpose: The incidence of ulcerated, bleeding, autologous, hemodialysis fistulas has been felt to be increasing in recent years. This review was undertaken to examine our experience with patients who presented with episodes of spontaneous bleeding in the presence of an ulcerated lesion over their autologous dialysis accesses.
Methods: A database of hemodialysis access procedures was reviewed for individuals with spontaneous bleeding from ulcerations. Twenty-four patients were identified with 28 ulcerating lesions over a ten-year period from 2001 to 2011. Each had at least a single episode of spontaneous bleeding. Treatment methods were reviewed including five techniques of surgical intervention.
Results: Two of 24 patients expired from major hemorrhagic events before obtaining surgical consultation (8.3%). Twenty-one patients (87.5%) underwent 28 surgical procedures for correction of the ulcers. One patient (4.1%) with simultaneous ulcers healed under antibiotic therapy during close observation in hospital. Simple suturing of the ulcer was found to be inconsistent in effectively maintaining hemostasis. Surgical excision of the ulcer with primary closure, vein patching of the fistula, or end-end anastomosis were equally effective in definitively correcting the problem.
Conclusions: The ulcerated autologous dialysis fistula is a life-threatening lesion and requires prompt surgical intervention to reduce mortality. The frequency of this problem appears to be increasing. Simple suturing of the ulcers was not consistently effective in remedying the problem and should be utilized as a temporizing measure until surgical correction can be undertaken. Fistulas can be uniformly salvaged with surgical intervention enabling uninterrupted dialysis treatments.
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http://dx.doi.org/10.5301/jva.5000001 | DOI Listing |
Radiology
November 2024
From the 2nd Department of Radiology, Interventional Radiology Unit, Attikon University General Hospital, 1st Rimini St, GR 12461 Chaidari, Athens, Greece (S.S., P.F., K.P., S.G., E.B., D.K.); Department of Nephrology and Hemodialysis Unit (I.E.G.) and Department of Interventional Radiology (E.B.), Mediterraneo Hospital, Glyfada, Greece; and Department of Interventional Radiology, School of Medicine, Patras University Hospital, Rion, Greece (K.K., P.K.).
Background Digital subtraction angiography and thrill palpation demonstrate limitations when used to assess the outcomes of angioplasty in autologous arteriovenous fistulas (AVFs). Purpose To investigate a new functional quantifiable index of successful angioplasty for failing AVFs using intraprocedural percutaneous US volume flow (VF) measurements. Materials and Methods This prospective, multicenter, single-arm, cohort clinical trial included consecutive patients with indications for fluoroscopically guided balloon angioplasty due to AVF dysfunction between June 2020 and May 2022.
View Article and Find Full Text PDFSichuan Da Xue Xue Bao Yi Xue Ban
September 2024
/ ( 610041) Department of Nephrology, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu 610041, China.
J Vasc Access
October 2024
AUSL Pescara, Interventional Nephrology Unit, Via Fonte Romana, Pescara, Italy.
Background: The development of a high flow rate arteriovenous fistula (AVF) can expose the patient to development of heart failure due to increased cardiac preload and pulmonary hypertension.
Objectives: AVF flow measurement (Qa) is considered a screening tool for AVF surveillance, aiming to evaluate the access dysfunction and prevent complications, like a non-maturation, suspected stenosis, high-flow AVF, and distal ischemia. In the upper arm AVF, a high Qa may develops, which can expose the patient to the risk of high-output heart failure and ischemia.
J Clin Med
September 2024
Department of Nephrology, Dialysis and Kidney Transplantation, Clinical Hospital Center Rijeka, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.
Regenerative medicine shows significant potential in treating kidney diseases through the application of various types of stem and progenitor cells, including mesenchymal stem cells (MSCs), renal stem/progenitor cells, embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). Stem cells possess the unique ability to repair injured organs and improve impaired functions, making them a key element in the research of therapies for kidney tissue repair and organ regeneration. In kidney transplantation, reperfusion injury can cause tissue destruction, leading to an initially low glomerular filtration rate and long-term impact on function by creating irreversible interstitial fibrosis.
View Article and Find Full Text PDFNatl Med J India
October 2024
Department of Pathology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India.
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