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Development and Validation of the Scale of Hypoglycemia Self-Care Behavior in Type 2 Diabetes.
Nurs Res
January 2025
Kaohsiung Medical University, College School of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung, Taiwan.
Background: Inappropriate dietary, exercise, and medication self-care behaviors among persons with diabetes can easily trigger hypoglycemia. Clinically, it is necessary to quickly identify high-risk groups for hypoglycemic events to provide targeted hypoglycemia education. However, there is currently a lack of precise tools to assess self-care behaviors related to hypoglycemia.
View Article and Find Full Text PDFThe Relationships of Workplace Spirituality and Psychological Capital with Work Engagement Among Junior High School Teachers.
Behav Sci (Basel)
January 2025
Department of Human Resource Development, National Kaohsiung University of Science and Technology, Kaohsiung 824004, Taiwan.
Engaged teachers demonstrate high levels of motivation and commitment to their work, increasing the likelihood of job retention and enabling them to perform at their best, ultimately benefiting both schools and students. Teacher engagement may be fostered by enhancing workplace spirituality and psychological capital. This study aimed to examine the relationships between and effects of workplace spirituality and psychological capital on work engagement, while also comparing demographic differences affecting these variables.
View Article and Find Full Text PDFLactic acid in the vaginal milieu modulates the -host interaction.
Virulence
December 2025
Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, T he Netherlands.
Vulvovaginal candidiasis (VVC) is one of the most common infections caused by . VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated with colonization of the vaginal mucosa. Compared to other host niches in which can cause infection, the vaginal environment is extremely rich in lactic acid that is produced by the vaginal microbiota.
View Article and Find Full Text PDFA post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
bioRxiv
January 2025
Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands.
Coronaviruses (CoV) encode sixteen non-structural proteins (nsps), most of which form the replication-transcription complex (RTC). The RTC contains a core composed of one nsp12 RNA-dependent RNA polymerase (RdRp), two nsp8s and one nsp7. The core RTC recruits other nsps to synthesize all viral RNAs within the infected cell.
View Article and Find Full Text PDFPharmacologic Management of Heart Failure with Preserved Ejection Fraction (HFpEF) in Older Adults.
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Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, 420 East 70th St, New York, NY, LH-36510063, USA.
There are several pharmacologic agents that have been touted as guideline-directed medical therapy for heart failure with preserved ejection fraction (HFpEF). However, it is important to recognize that older adults with HFpEF also contend with an increased risk for adverse effects from medications due to age-related changes in pharmacokinetics and pharmacodynamics of medications, as well as the concurrence of geriatric conditions such as polypharmacy and frailty. With this review, we discuss the underlying evidence for the benefits of various treatments in HFpEF and incorporate key considerations for older adults, a subpopulation that may be at higher risk for adverse drug events.
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