Neuromagnetic cerebellar activation during seizures arising from the motor cortex.

Epilepsy Res

Department of Pediatrics, IWK Health Center, Dalhousie University, 5850/5980 University Ave., Halifax, NS, Canada.

Published: October 2011

We utilized the high temporal resolution, whole head coverage and novel analysis methodology of magnetoencephalography (MEG) to record the dynamics of cerebellar activation during focal motor seizures. We analyzed ictal MEG data from a four-year old using an event-related beamformer to localize and display ictal changes over the motor cortex and cerebellum. Contralateral activation of the cerebellum was seen 14s after MEG ictal onset over the motor cortex. These findings represent the first indication of ictal activity within the cerebellum in humans, measured non-invasively with MEG.

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http://dx.doi.org/10.1016/j.eplepsyres.2011.06.003DOI Listing

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