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Antireflux surgery - choosing the right candidate.
Expert Rev Gastroenterol Hepatol
January 2025
Department of Gastroenterology & Hepatology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Introduction: Surgical gastric fundoplication is an effective treatment option for gastroesophageal reflux disease. In contrast to acid suppression, fundoplication nearly abolishes all types of reflux, acid and nonacid. However, in some cases lasting side effects of the procedure may overshadow its positive effects.
View Article and Find Full Text PDFAtypical presentation of an epiphrenic esophageal diverticulum 20 years post fundoplication: a case report and review.
J Surg Case Rep
May 2024
Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United States.
Esophageal diverticulum is a rare condition characterized by the herniation of the esophageal mucosa outside the esophageal wall. Here, we explore the prevalence of ED and its associated esophageal dysmotility. We also shed light on the potential impact of previous surgical interventions, such as Nissen's fundoplication, on the development of ED.
View Article and Find Full Text PDFEfficacy and safety of tegoprazan in the treatment of gastroesophageal reflux disease: A protocol for meta-analysis and systematic review.
PLoS One
May 2024
Thyroid -ENT Head and Neck Surgery Department, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.
Objective: The incidence of gastroesophageal reflux disease (GERD) is increasing year by year, the clinical manifestations are complex and diverse, and the adverse effects of long-term use of proton pump inhibitors and gastrointestinal motility drugs have been of great concern in recent years. The effectiveness of tegoprazan in the treatment of GERD is still controversial. This protocol describes a systematic review and meta-analysis to evaluate the efficacy and safety of tegoprazan in the treatment of gastroesophageal reflux disease.
View Article and Find Full Text PDFComparison of the efficacy of diltiazem versus fluoxetine in the treatment of distal esophageal spasm: A randomized-controlled-trial.
Arab J Gastroenterol
May 2024
Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 198571115, Iran. Electronic address:
Background And Study Aim: Distal esophageal spasm is an uncommon esophageal motility disorder presenting with non-cardiac chest pain and dysphagia. The main goal of therapy is symptom relief with pharmacologic, endoscopic, and surgical therapies. Pharmacologic treatment is less invasive and is the preferred method of choice.
View Article and Find Full Text PDFCurrent self-medication practices in the Kingdom of Saudi Arabia: an observational study.
Pan Afr Med J
January 2021
Faculty of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Introduction: medication without prescription is a growing public health concern or phenomenon worldwide. This cross-sectional study was designed to study the trends of self-medication among Saudi population.
Methods: a prospective, cross-sectional study including 2004 participants was carried out from different family clinics across the Kingdom of Saudi Arabia (KSA).
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