Obesity is an increasing problem both in the United States and South Dakota. Currently, 30.3 percent of South Dakota adults self-report being obese, which is higher than the national prevalence and also increasing at a faster rate than other states. The obesity rate for South Dakota 2- to 5-year-olds from limited-income households is 16.4 percent and above the national prevalence. Obesity prevalence among students Kindergarten through grade 12 was 16.0 percent for the 2009-2010 school year, not higher than national data.
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Mol Genet Metab Rep
March 2025
Hayward Genetics Center, Dept of Pediatrics, Tulane University Medical School, New Orleans, LA, USA.
Objective: To provide insights and strategies for pegvaliase management in challenging cases with phenylketonuria (PKU) based on the first 5 years of experience with pegvaliase in real-world clinical practice.
Methods: Twelve PKU experts gathered during a one-day, in-person meeting to discuss clinical cases illustrating important lessons from their experiences treating patients with pegvaliase in real-world clinical practice. Challenges with pegvaliase experienced prior to and during treatment and corresponding strategies to overcome them were discussed.
J Gastrointest Oncol
December 2024
Department of Interventional Vascular Surgery, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.
Background: Hepatocellular carcinoma (HCC) constitutes approximately 75-85% of primary liver cancers and is a heavy burden on public health. Many innovative prediction systems have integrated radiomics, artificial intelligence, pathological information, or even genetic information for the stratification and prognosis prediction of patients with HCC. However, these systems still lack practical and clinical applications.
View Article and Find Full Text PDFNature
January 2025
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
During motor learning, breaks in practice are known to facilitate behavioural optimizations. Although this process has traditionally been studied over long breaks that last hours to days, recent studies in humans have demonstrated that rapid performance gains during early motor sequence learning are most pronounced after very brief breaks lasting seconds to minutes. However, the precise causal neural mechanisms that facilitate performance gains after brief breaks remain poorly understood.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
U.S. Geological Survey, Forest and Rangeland Ecosystem Science Center, 3200 SW Jefferson Way, Corvallis, Oregon 97331, United States.
Significant variation in mercury (Hg) bioaccumulation is observed across the diversity of freshwater ecosystems in North America. While there is support for the major drivers of Hg bioaccumulation, the relative influence of different external factors can vary widely among waterbodies, which makes predicting Hg risk across large spatial scales particularly challenging. We modeled Hg bioaccumulation by coupling Hg concentrations in more than 21,000 dragonflies collected across the United States from 2008 to 2021 with a suite of chemical (e.
View Article and Find Full Text PDFWorld Psychiatry
February 2025
School of Health in Social Science, University of Edinburgh, Edinburgh, UK.
Feeding and eating disorders (FEDs) are a heterogeneous grouping of disorders at the mind-body interface, with typical onset from childhood into emerging adulthood. They occur along a spectrum of disordered eating and compensatory weight management behaviors, and from low to high body weight. Psychiatric comorbidities are the norm.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!