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[Pneumocystis pneumonia].
Klin Mikrobiol Infekc Lek
September 2023
Clinic of Infectious Diseases, Faculty of Medicine, Masaryk University, University Hospital Brno, Czech Repubic, e-mail:
In parallel with the introduction of modern therapeutic and pharmacological interventions that have successfully resolved many diseases and conditions, previously deemed incompatible with life, there has been a significant increase in the number of patients experiencing secondary immunodeficiency. As a result, these patients are highly susceptible to various opportunistic infections. Among these infections, pneumocystis pneumonia (PCP) stands out as one of the most frequent and potentially life-threatening ones, necessitating prompt diagnosis and treatment.
View Article and Find Full Text PDF[Effect of enzybiotics on the healing of Staphylococcus aureus-infected skin wounds in a pig model].
Klin Mikrobiol Infekc Lek
March 2024
Department of Infectious Diseases and Preventive Medicine, Research Institute of Veterinary Medicine, Brno, Czech Republic, e-mail:
Introduction: Staphylococcus aureus is a gram-positive, facultatively anaerobic coccus capable of causing infectious diseases in animals and humans. Especially dangerous are multidrug-resistant forms with poor or even no response to available treatments.
Objectives: The study aimed to verify the effect of enzybiotics on the healing of S.
Selective progesterone receptor modulators for the treatment of dysmenorrhea: an update.
Expert Opin Pharmacother
January 2025
Department of Obstetrics and Gynecology, University of Florence, Careggi University Hospital, Florence, Italy.
Introduction: Dysmenorrhea is a painful symptom associated with uterine contractions and menstrual bleeding and is treated by administering analgesic drugs. Since progesterone receptors (PRs) have a major role in regulating uterine tissues (myometrium and endometrium) oral contraceptives are used off-label for treating primary or secondary dysmenorrhea. The development of selective progesterone receptor modulators (SPRMs) a class of synthetic steroids with agonistic, antagonistic, or mixed effects in targeting PRs in different tissues stimulated their possible clinical use for treating secondary dysmenorrhea related to uterine diseases (endometriosis, adenomyosis, uterine fibroids).
View Article and Find Full Text PDFUse of vortioxetine in different neurological fields: a systematic review and future perspectives.
Neurol Sci
January 2025
Department of Neurology, Provincial Hospital of Bolzano (SABES- ASDAA), Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversität, Bolzano, 39100, Italy.
Introduction: Vortioxetine is a multimodal antidepressant with a high tolerability profile. Recent evidence suggests a role for vortioxetine in improving cognitive function and reducing functional disability linked to depression. We conducted a systematic review on the use of vortioxetine in different neurological disorders.
View Article and Find Full Text PDFVariations in wheat water requirement and climatic causes in arid regions of northwest China.
Environ Monit Assess
January 2025
School of Energy and Power Engineering, Xihua University, No. 9999 Hongguang Street, Chengdu, 610039, Sichuan Province, China.
Analysis of crop water requirement and its influencing factors are important for optimal allocation of water resources. However, research on variations of climatic factors and their contribution to wheat water requirement in Xinjiang is insufficient. In our study, daily meteorological data during 1961‒2017 in Xinjiang was collected.
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