Purpose: For the treatment of some cancerous tumors using brachytherapy, an American Association of Physicists in Medicine (AAPM) Task Group No. 43U1 report recommends that the dosimetric parameters of a new brachytherapy source must be determined in two experimental and Monte Carlo theoretical methods before using each new source clinically. This study presents the results of Monte Carlo calculations of the dosimetric parameters for a Ir2.A85-2 brachytherapy source design.
Materials And Methods: Version 5 of the (MCNP) Monte Carlo radiation transport code was used to calculate the dosimetry parameters around the source.
Results: The Monte Carlo calculated dose rate constant, Λ, of the Ir2.A85-2 source was found to be 1.113 ± 0.033 cGyU(-1)h(-1). Also in this study, the line-source radial dose function, g ( l )(r) and the anisotropy function, F(r,θ), have been calculated at distances from 0.5 to 10 cm. The results of these calculations have been compared with the published data for the same source.
Conclusion: All the results are in good concordance with previously published data, with a few exceptions in small angles and short distances. The dosimetric parameters calculated in this work can be used as input data in a treatment planning system (TPS) for exact brachytherapy treatment planning or to verify the calculations of the TPS used in brachytherapy.
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http://dx.doi.org/10.1007/s11604-011-0562-1 | DOI Listing |
Med Phys
January 2025
Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Background: A cylindrical free-air chamber, the Attix FAC, is used for absolute air-kerma measurements of low-energy photon beams at the University of Wisconsin Medical Radiation Research Center. Correction factors for air-kerma measurements of specific beams were determined in the 1990s. In order to measure air-kerma rates of beams in development, new correction factors must be computed.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
January 2025
Maebashi-Institute of Technology, Systems Life Engineering, Gunma, 371-0816 Japan. Electronic address:
Introduction: The successful diagnosis and treatment of early-stage breast cancer enhances the quality of life of patients. As a promising alternative to recently developed magnetic resonance imaging-guided radiotherapy, we proposed fluorescence molecular imaging-guided photodynamic therapy (FMI-guided PDT), which requires no expensive equipment. In the FMI simulations, ICG-C11 which has emission peaks at near-infrared wavelengths was used as the FMI agent.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, PR China; Faculty of Architecture, The University of Hong Kong, Hong Kong, PR China. Electronic address:
Infectious microbes can spread rapidly from fomites (contaminated surfaces) via hand touch, with prolonged residence time on surfaces increasing transmission risk by extending exposure periods and/or involving more susceptible individuals. Existing studies have focused on decreasing microbial contamination, but not on the need for rapid removal from surface systems. This study introduces residence time as the time that a microbe spends within the surface system.
View Article and Find Full Text PDFUltramicroscopy
January 2025
Mechanical Engineering, University of Michigan, USA.
The objective of this work was to explore the capabilities of a field emission gun scanning electron microscope (FEG-SEM) equipped with a transmission scanning electron detector (TSEM) and energy dispersive spectroscopy (EDS) to identify nanoscale chemical heterogeneities in a gas atomization reaction synthesis (GARS) steel sample. The results of this analysis were compared to the same study conducted with scanning transmission electron microscopy (STEM) with EDS mapping. TSEM-EDS was performed using the standard spectral analysis approach, i.
View Article and Find Full Text PDFJ Mol Model
January 2025
Processes, Materials and Environment Laboratory (LPME), Faculty of Sciences and Technology of Fez, Sidi Mohamed Ben Abdellah University, B.P. 2202, Fez, Morocco.
Context: Natural fluorapatite (FAP) has been investigated as an adsorbent for the removal of dyes such as methylene blue (MB) and crystal violet (CV) from aqueous solutions. Effective dye removal is crucial for water treatment, particularly for industrial wastewater containing toxic dyes. FAP, a naturally abundant material, was characterized using XRD, FTIR, and SEM analysis.
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