High pixel count apertures for digital holography may be synthesized by scanning smaller aperture detector arrays. Characterization and compensation for registration errors in the detector array position and pitch and for phase instability between the reference and object field is a major challenge in scanned systems. We use a secondary sensor to monitor phase and image-based registration parameter estimators to demonstrate near diffraction-limited resolution from a 63.4 mm aperture synthesized by scanning a 5.28 mm subaperture over 144 transverse positions. We demonstrate 60 μm resolution at 2 m range.
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http://dx.doi.org/10.1364/OE.19.011716 | DOI Listing |
J Immunother Cancer
January 2025
Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China
Background: Numerous studies have demonstrated limited survival benefits of transarterial chemoembolization (TACE) alone in the treatment of intermediate-stage hepatocellular carcinoma (HCC) beyond up-to-seven criteria. The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has opened new avenues for HCC treatment. However, TACE combined with ICIs has not been investigated for patients with intermediate-stage HCC beyond the up-to-seven criteria.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Excellence Center for Hip & Knee Arthroplasty, Department of Orthopedic Surgery, Zuyderland Medical Center, Heerlen, The Netherlands.
Introduction: In 2020, 368 million people globally were affected by knee osteoarthritis, and prevalence is projected to increase with 74% by 2050. Relatively high rates of dissatisfactory results after total knee arthroplasty (TKA), as reported by approximately 20% of patients, may be caused by sub-optimal knee alignment and balancing. While mechanical alignment has traditionally been the goal, patient-specific alignment strategies are gaining interest.
View Article and Find Full Text PDFPhys Med Biol
January 2025
School of Software Engineering, Xi'an Jiaotong University, Xi 'an Jiaotong University Innovation Port, Xi 'an, Shaanxi Province, Xi'an, Shaanxi, 710049, CHINA.
Deformable registration aims to achieve nonlinear alignment of image space by estimating a dense displacement field. It is commonly used as a preprocessing step in clinical and image analysis applications, such as surgical planning, diagnostic assistance, and surgical navigation. We aim to overcome these challenges: Deep learning-based registration methods often struggle with complex displacements and lack effective interaction between global and local feature information.
View Article and Find Full Text PDFPurpose: With the widespread introduction of dual energy computed tomography (DECT), applications utilizing the spectral information to perform material decomposition became available. Among these, a popular application is to decompose contrast-enhanced CT images into virtual non-contrast (VNC) or virtual non-iodine images and into iodine maps. In 2021, photon-counting CT (PCCT) was introduced, which is another spectral CT modality.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
Amsterdam UMC location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
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