Placental abruption, offspring sex, and birth outcomes in a large cohort of mothers.

J Matern Fetal Neonatal Med

Department of Preventive Medicine & Institute for Global Health, Vanderbilt University, Nashville, TN, USA.

Published: March 2012

AI Article Synopsis

  • The study aimed to examine stillbirth, neonatal, and perinatal death rates in pregnancies affected by placental abruption, focusing on the sex of the fetus.
  • Researchers analyzed data from over 10,000 singleton live births from 1989 to 2005, finding a higher incidence of placental abruption in pregnancies with male infants compared to females, while clarifying that the fetal sex did not significantly affect survival rates.
  • The results indicated that although more male infants were born to mothers with placental abruption, both sexes had similar outcomes regarding stillbirth, neonatal mortality, and perinatal mortality.

Article Abstract

Objective: To investigate stillbirth, neonatal, and perinatal death outcomes in pregnancies complicated by placental abruption, according to fetal sex.

Methods: We utilized maternally linked cohort data files of singleton live births to mothers diagnosed with placental abruption during the period 1989 through 2005 (n = 10,014). Logistic regression models were employed to generate adjusted odd ratios and their 95% confidence intervals. Male babies served as the referent category.

Results: The sex ratio at birth was 1.18. The overall prevalence of stillbirth, neonatal mortality, and perinatal mortality was 7.2%, 4.5%, and 11.8%, respectively. Placental abruption was less likely to occur in mothers carrying female pregnancies than mothers of male infants (adjusted odds ratio [95% confidence interval] = 0.89 [0.86-0.93]). There were no significant sex differences with regards to stillbirth, neonatal mortality, and perinatal mortality. Similar findings were observed for preterm and term infants.

Conclusions: Although a preponderance of male infants was discernable among mothers with placental abruption, no sex difference in fetal survival was observed among the offspring of the mothers affected by placental abruption.

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http://dx.doi.org/10.3109/14767058.2011.569615DOI Listing

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