AI Article Synopsis
- The study discusses complex cases of fetal anemia, focusing on appropriate investigations and management strategies.
- Four specific cases are highlighted, including one neonatal death, a pregnancy termination, a case of Diamond Blackfan anemia, and a case related to feto-maternal hemorrhages.
- Non-alloimmune fetal anemia presents significant management challenges, often requiring frequent intrauterine transfusions, and is associated with higher perinatal mortality and preterm delivery rates.
Article Abstract
Objectives: To describe a series of complex fetal anemia cases, detail the appropriate investigations and management, and review the literature.
Methods: Four cases of non-red cell alloimmunization or infective cases of fetal anemia are presented.
Results: Of the four cases presented, one was a neonatal death, one pregnancy was terminated, one case was diagnosed with Diamond Blackfan anemia, and one case was due to recurrent feto-maternal hemorrhages despite negative Kleihauer tests.
Conclusions: Non-alloimmune causes of fetal anemia can be difficult to manage. Some cases require repeated and frequent intrauterine transfusions. The perinatal mortality and preterm delivery rates are increased, and some cases require considerable long-term treatment including regular transfusions. We present our experience of a series of non-immune fetal anemia managed in a tertiary unit, review the literature, and suggest appropriate management.
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| http://dx.doi.org/10.3109/14767058.2010.551149 | DOI Listing |
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