Aim: The aim of the research was to construct a questionnaire basing on the presently standing criteria of sexual dysfunctions and sexual disorders (according to ICD-10), that would enable the diagnosis of symptoms, as well as to verify its validity.
Method: 102 patients (46 women and 56 men, mean age of 32.09, SD = 10.29) of sexological clinics who declared they had symptoms of sexual dysfunctions or disorders were asked to participate and fill in the questionnaire which was later evaluated in a clinical study on the basis of ICD-10 research criteria.
Results: Results show that using the questionnaire enables the diagnosis of 100% of gender identity disorders, almost all sexual dysfunctions and disorders connected to sexual orientation. The sensibility and specificity of the questionnaire were also examined and proved very high.
Conclusions: The Sexological questionnaire for screening research presents with good validity, sensibility and specificity.
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Front Immunol
January 2025
Department of Urology, Jiangsu Provincial People's Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: Erectile dysfunction (ED) is a prevalent male sexual disorder, commonly associated with hypertension, though the underlying mechanisms remain poorly understood.
Objective: This study aims to explore the role of Fatty acid synthase (Fasn) in hypertension-induced ED and evaluate the therapeutic potential of the Fasn inhibitor C75.
Materials And Methods: Erectile function was assessed by determining the intracavernous pressure/mean arterial pressure (ICP/MAP) ratio, followed by the collection of cavernous tissue for transcriptomic and non-targeted metabolomic analyses.
Nervenarzt
January 2025
Klinik für Psychiatrie und Psychotherapie, Asklepios Fachklinikum Tiefenbrunn, Deutschland37124, Rosdorf, Deutschland.
Background: Disorders of sexual function are a frequent comorbidity of depression and have complex interactions on psychological, sexual and relationship qualities.
Objective: To determine the prevalence of sexual functional disorders in depressed patients, the effects of antidepressant drugs and development of treatment recommendations.
Material And Method: Evaluation of the current literature and discussion of fundamental studies.
Eur J Trauma Emerg Surg
January 2025
Faculty of Medicine, University of Zurich, Raemistrasse 71, 8006, Zurich, Switzerland.
Introduction: Pelvic ring fractures are known to be associated with complications associated with adjacent organ injuries, such as the urogenital tract (e.g. erectile dysfunction (ED), which are sometimes diagnosed in a delayed fashion.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
The Second Department of Infectious Disease, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Background: Erectile dysfunction (ED) is characterized by the inability to achieve or maintain penile erection sufficient for intercourse. While previous research suggests a potential link between ED and prostate pathologies, the association between benign prostatic hyperplasia (BPH), prostatitis, prostatic cancer (PCa), and ED remains to be elucidated.
Methods: Data from participants (40-80 years, n=2225) were extracted from the NHANES 2001-2004 for this observational study.
Biol Res
January 2025
Department of Urology and Andrology, Renji Hospital, Shanghai Institute of Andrology, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China.
Background: Cavernous nerve injury-induced erectile dysfunction (CNI-ED) is a common complication following radical prostatectomy and severely affects patients' quality of life. The mitochondrial impairment in corpus cavernosum smooth muscle cells (CCSMCs) may be an important pathological mechanism of CNI-ED. Previous studies have shown that transplantation of human adipose derived stem cells (ADSC) can alleviate CNI-ED in a rat model.
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