The present study compared the Eating Disorder Examination (EDE; 16.0) and the Eating Disorder Examination-Questionnaire (EDE-Q; 6.0) and investigated the psychometric properties of the Norwegian translation of the EDE. Fifty-eight university women aged 19-41 years (mean BMI = 23) were assessed with the EDE and EDE-Q. Satisfactory internal consistency and inter-rater reliability were demonstrated for the Norwegian translation of the EDE. Generally high convergent validity between the EDE and EDE-Q was found, with correlations ranging from 0.60 (Eating Concern) to 0.86 (Weight Concern). Agreement for OBEs and vomiting were excellent, while driven exercising generated lower levels of convergence. Consistent with prior studies, the EDE-Q generated significantly higher levels of psychopathology, although effect sizes were small. Owing to the significantly higher EDE-Q scores, it is ill advised to administer these two instruments interchangeably, as this may fail to produce meaningful data.
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http://dx.doi.org/10.1002/erv.1068 | DOI Listing |
Glucagon-like peptide-1 receptor agonists (GLP1RAs) effectively reduce body weight and improve metabolic outcomes, yet established peptide-based therapies require injections and complex manufacturing. Small-molecule GLP1RAs promise oral bioavailability and scalable manufacturing, but their selective binding to human versus rodent receptors has limited mechanistic studies. The neural circuits through which these emerging therapeutics modulate feeding behavior remain undefined, particularly in comparison to established peptide-based GLP1RAs.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
January 2025
Translational Developmental Neuroscience Section, Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany; Eating Disorder Treatment and Research Center, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany. Electronic address:
Background: The thalamus is a complex subcortical brain structure that plays a role in various cognitive functions. Few studies have focused on thalamic nuclei-specific alterations and potential neurohormonal involvement in eating disorders including anorexia nervosa (AN).
Methods: We employed a FreeSurfer segmentation tool to compare thalamic nuclei volumes cross-sectionally between females with AN (n = 131, 12-29 years) and age-matched healthy females (HC, n = 131).
Andes Pediatr
October 2024
Facultad de Medicina Occidente, Universidad de Chile, Santiago, Chile.
Polycystic Ovary Syndrome (PCOS) is the most common endocrine-metabolic disorder in female adolescents, and it is associated with metabolic, cardiovascular, and reproductive complications. Recent findings also suggest an association with psychiatric pathology, both affected patients and their offspring. In this update, we synthesized the recent literature on mental health in women and adolescents with PCOS through a systematic search in PubMed, Epistemonikos, and Scielo for articles published in the last 5 years.
View Article and Find Full Text PDFAndes Pediatr
August 2024
Departamento de Pediatría y Cirugía Infantil, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Unlabelled: Among the restrictive eating and eating disorders, anorexia nervosa (AN) and atypical anorexia nervosa (AAN) are the ones that present the greatest medical complications.
Objective: Describe the characteristics of patients with AN and AAN and their differences in demographic and clinical parameters.
Patients And Method: The records of patients <19 years of age with AN admitted to Clinica Santa María between 2013 and 2019 were reviewed.
Int J Eat Disord
January 2025
The Eating Disorders and Autism Collaborative (EDAC), University of Edinburgh, Edinburgh, UK.
Objective: Avoidant/restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by extensive avoidance and/or restriction of food. Existing research demonstrates that ARFID is over-represented in Autistic populations and vice-versa, with both groups exhibiting shared characteristics. This meta-analysis investigated the co-occurrence between ARFID and autism via determination of autism prevalence in ARFID populations, and ARFID prevalence in Autistic groups.
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