AI Article Synopsis
- A study involving 100 patients with late effects from closed craniocerebral injuries (CCCI) and 50 healthy individuals was conducted to analyze genetic and clinical factors.
- It was found that patients showed a higher occurrence of multifactorial diseases, particularly essential hypertension and cardiovascular issues, in their family histories compared to the healthy group.
- Additionally, many patients exhibited signs of developmental abnormalities and some developed hereditary diseases after their injuries, suggesting that genetic risk factors are important for predicting outcomes and managing follow-up care for CCCI patients.
Article Abstract
As many as 100 patients with late sequelae of closed craniocerebral injuries (CCCI) and 50 healthy persons underwent a clinico-genealogical and phenotypic analysis. Multifactorial diseases (in particular essential hypertension and other cardiovascular diseases) which correlate with the clinical features of late sequelae of CCCI were noted to occur in the patients' pedigree significantly more often as compared to normal persons. The patients manifest a high frequency of the stigmas of dysembryogenesis. After CCCI part of them manifested certain hereditary diseases. Genetic risk factors should be taken into account in forecasting CCCI outcomes and planning follow up measures.
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