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http://dx.doi.org/10.1186/cc10149 | DOI Listing |
J Cardiovasc Transl Res
January 2025
Cardiac Regeneration and Ageing Lab, Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, 226011, China.
HFpEF is a prevalent and complex type of heart failure. The concurrent presence of conditions such as obesity, hypertension, hyperglycemia, and hyperlipidemia significantly increase the risk of developing HFpEF. Mitochondria, often referred to as the powerhouses of the cell, are crucial in maintaining cellular functions, including ATP production, intracellular Ca regulation, reactive oxygen species generation and clearance, and the regulation of apoptosis.
View Article and Find Full Text PDFSheng Wu Gong Cheng Xue Bao
January 2025
College of Pharmacy and Life Sciences, Jiujiang University, Jiujiang 332000, Jiangxi, China.
There is a large gap between production and demand of plant oil in China, which leads to the heavy reliance on imports. Diacylglycerol acyltransferase (DGAT) and phospholipid: diacylglycerol acyltransferase (PDAT) are two key enzymes responsible for the synthesis of triacylglycerol, thereby affecting the yield and quality of plant oil. This paper comprehensively reviews the research progress in and in terms of their biological functions in plant oil synthesis, the molecular mechanisms of regulating plant lipid metabolism, growth, and development under stress, and their roles in driving oil synthesis under the background of synthetic biology.
View Article and Find Full Text PDFJ Assist Reprod Genet
January 2025
Center of Reproductive Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Background: The 12-h ultradian rhythm plays a crucial role in metabolic homeostasis, but its role in ovarian aging has not been explored. This study investigates age-related changes in 12-h rhythmic gene expression across various human tissues, with a particular focus on the ovary.
Methods: We analyzed transcriptomic data from the GTEx project to examine 12-h ultradian rhythmic gene expression across multiple peripheral human tissues, exploring sex-specific patterns and age-related reprogramming of both 12-h and 24-h rhythmic gene expression.
Quant Imaging Med Surg
January 2025
Department of Nuclear Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background And Objective: Orthopedic prostheses have become increasingly prevalent in clinical practice in recent years. However, orthopedic prosthesis-associated infections (OPAI) have emerged as a serious complication associated with their use. Due to the variety of orthopedic implant types and the atypical clinical manifestations of OPAI, it is easy to cause delayed diagnosis and affect the prognosis of patients.
View Article and Find Full Text PDFZhonghua Yu Fang Yi Xue Za Zhi
January 2025
Department of Emergency Medicine, The Sixth Medical Center of PLA General Hospital, Beijing100048, China.
Dog and cat bites are the most common types of animal injuries, which cause various types of tissue damage and have a high incidence of wound infections. These infections are often mixed with multiple microorganisms and have their characteristics and complexity. Selecting appropriate antimicrobial drugs for prevention and treatment can help prevent the occurrence of infections and improve the effectiveness of infection treatment.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!