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The Influence of Sex, Fitness, BMI, and Cardiovascular Risk Factors on Cerebral Blood Velocity Responsiveness to Graded Exercise Testing in Middle-Aged Adults.
J Gerontol A Biol Sci Med Sci
December 2024
GENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo, Spain.
Mean middle cerebral artery velocity (MCAv) and the pulsatility index (PI), at rest and in response to exercise, are important markers of cerebrovascular health status in middle-aged adults, when vascular decline assumes substantial relevance. Thus, this study aimed to describe and compare the responses of MCAv and PI to incremental exercise. Two hundred and forty-eight volunteers (50-58 years, 55% women) completed a ramp test on a cycle-ergometer.
View Article and Find Full Text PDFArtificial Intelligence in Transcranial Doppler Ultrasonography.
Curr Med Imaging
January 2025
UOC Neurologia e Rete Stroke Metropolitana, Istituto delle Scienze Neurologiche di Bologna, Italy.
Transcranial Doppler is an instrumental ultrasound method capable of providing data on various brain pathologies, in particular, the study of cerebral hemodynamics in stroke, quickly, economically, and with repeatability of the data themselves. However, literature reviews from clinical studies and clinical trials reported that it is an operator-dependent method, and the data can be influenced by external factors, such as noise, which may require greater standardization of the parameters. Artificial intelligence can be utilized on transcranial Doppler to increase the accuracy and precision of the data collected while decreasing operator dependencies.
View Article and Find Full Text PDFTranscranial Doppler Arterial Pressure Gradient Is Associated With Delayed Infarction After Subarachnoid Hemorrhage.
J Neuroimaging
January 2025
Department of Neurology, Georgetown University School of Medicine, Washington, District of Columbia, USA.
Background And Purpose: While the pulsatility index (PI) measured by transcranial Doppler (TCD) has broader associations with outcomes in neurocritical care, its use in monitoring delayed cerebral infarction (DCI) in patients with aneurysmal subarachnoid hemorrhage (SAH) is not endorsed by current clinical guidelines. Recognizing that arterial pressure gradient (ΔP) can be estimated using PI, we investigated the potential significance of TCD-estimated ΔP.
Methods: In this observational study of 186 SAH patients, we recorded the mean cerebral blood flow velocity (mCBFV) and PI values from the middle cerebral artery, along with corresponding blood pressures.
Does age, sex, and area of substantia nigra echogenicity predict the MRI appearance of nigrosome-1?
J Neurol Sci
January 2025
UniSA Clinical & Health Sciences and Alliance for Research in Exercise, Nutrition and Activity (ARENA), City East Campus, University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia. Electronic address:
The appearance of the substantia nigra (SN) can aid diagnosis of Parkinson's disease (PD). The effect of age and sex on the appearance of nigrosome-1 (SN subregion) on magnetic resonance imaging (MRI), and the relationship between nigrosome-1 (viewed with MRI) and SN echogenicity (viewed with transcranial ultrasound) is unknown. The study aimed to address these knowledge gaps.
View Article and Find Full Text PDFAnalysis of blood flow velocity variability in middle cerebral artery stenosis using transcranial color-coded sonography.
J Clin Neurosci
January 2025
Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, PR China.
Background: High variability of intracranial arterial blood flow velocities by Transcranial color-coded sonography (TCCS) has been found in clinical practice. This study aimed to improve diagnostic accuracy by analyzing influencing factors of middle cerebral artery (MCA) blood flow velocity detected by TCCS.
Methods: In total, 328 MCA vessels were classified as normal (27.
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