Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165500PMC
http://dx.doi.org/10.1128/JB.05378-11DOI Listing

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