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Crosstalk between fat tissue and muscle, brain, liver, and heart in obesity: cellular and molecular perspectives.
Eur J Med Res
December 2024
Graduate School of Education, Shandong Sport University, Jinan, Shandong, China.
A high-fat diet and physical inactivity are key contributors to obesity, predisposing individuals to various chronic diseases, such as cardiovascular disease and diabetes, which involve multiple organs and tissues. To better understand the role of multi-organ interaction mechanisms in the rising incidence of obesity and its associated chronic conditions, treatment and prevention strategies are being extensively investigated. This review examines the signaling mechanisms between different tissues and organs, with a particular focus on the crosstalk between adipose tissue and the muscle, brain, liver, and heart, and potentially offers new strategies for the treatment and management of obesity and its complications.
View Article and Find Full Text PDFPerceptions of dental professionals on the use of silver diamine fluoride with or without light-curing.
BMC Oral Health
December 2024
Department of Community Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henri-Dunant rd., Wangmai, Pathumwan, Bangkok, 10330, Bangkok, Thailand.
Background: According to anecdotal reports, SDF's ability to arrest caries can be enhanced by light-curing in a clinical setting. The purpose of the present study was to explore the dental professionals' perceptions of using SDF and to understand the barriers and enabling factors to using SDF with and without light-curing.
Methods: A qualitative study was conducted with dental professionals who had experience with using SDF with and without light-curing.
Aberrant resting-state functional network centrality and cognitive impairment in unmedicated, euthymic bipolar patients.
BMC Psychiatry
December 2024
Department of Geriatric Psychiatry, Suzhou Mental Health Center, Suzhou Guangji Hospital, the Affiliated Guangji Hospital of Soochow University, Suzhou, China.
Background: Cognitive impairment is prevalent in bipolar disorder (BD), and has negative impacts on functional impairments and quality of life, despite euthymic states in most individuals. The underlying neurobiological basis of cognitive impairment in BD is still unclear.
Methods: To further explore potential connectivity abnormalities and their associations with cognitive impairment, we conducted a degree centrality (DC) analysis and DC (seed)-based functional connectivity (FC) approach in unmedicated, euthymic individuals with BD.
Cigarette smoking is associated with reduced neuroinflammation and better cognitive control in people living with HIV.
Neuropsychopharmacology
January 2025
Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
People living with HIV (HIV+) are roughly twice as likely to smoke cigarettes (Smok+) as the general population. With the advent of effective antiretroviral therapies, it is increasingly important to understand the effects of chronic HIV infection and cigarette smoking on brain function and cognition since HIV+ individuals have heightened neuroinflammation and cognitive deficits even with such therapies. Based on prior studies demonstrating that smoking reduces a marker for neuroinflammation in HIV- individuals, we hypothesized that HIV+/Smok+ individuals would have less neuroinflammation and better cognitive control than HIV+/Smok- individuals.
View Article and Find Full Text PDFLight People: Prof. Henry Snaith's (FRS) perovskite optoelectronics journey.
Light Sci Appl
January 2025
Executive Management College of CHN ENERGY, No.7 Binhe Avenue, North District of Future Science City, Changping District, Beijing, 102211, China.
In 2012, Prof. Henry Snaith demonstrated the first solid-state perovskite solar cell (PSC) with an efficiency of 10.9%, igniting a surge of interest and research into perovskite materials for their potential to revolutionize the photovoltaic (PV) industry.
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