We are reporting two cases of chronic neuropathic pain after traumatism during regional anaesthesia (RA). Nerve injury is a rare complication of RA and it is the neurogical deficit, which is the most often quoted in medical literature. However, in both cases the neuropathic pain was the single departure point. The reunion of the clinical element, which incorporates possible traumatism during regional anaesthesia, characteristics of pain and unusual painful localization of surgery, should have allowed a more early diagnostic and treatment. In both cases, persistent neuropathic pain incapacitates the patient several years after the traumatism.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.annfar.2011.05.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Accumulation of advanced oxidative protein products exacerbate satellite glial cells activation and neuropathic pain.
Mol Med
January 2025
Division of Spine Surgery, Department of Orthopedics, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Ave, Guangzhou, 510515, People's Republic of China.
Background: Neuropathic pain (NP) is a debilitating condition caused by lesion or dysfunction in the somatosensory nervous system. Accumulation of advanced oxidation protein products (AOPPs) is implicated in mechanical hyperalgesia. However, the effects of AOPPs on NP remain unclear.
View Article and Find Full Text PDFUnveiling the Dichotomic Nature of VEGFA in neuropathic pain: A path to targeted therapeutics.
Neurotherapeutics
January 2025
Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL, USA; Pain Research and Integrated Neuroscience Center (PRINC), College of Medicine, University of Florida, Gainesville, FL, USA; McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, FL, USA. Electronic address:
TET1 participates in oxaliplatin-induced neuropathic pain by regulating microRNA-30b/Nav1.6.
J Biol Chem
January 2025
Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China; Institute of Neuroscience, School of Basic Medical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China; School of Nursing and Health, Zhengzhou University, 100 Science venue, Zhengzhou, 450001, China. Electronic address:
Chemotherapy-induced neuropathic pain poses significant clinical challenges and severely impacts patient quality of life. Sodium ion channels are crucial in regulating neuronal excitability and pain. Our research indicates that the microRNA-30b (miR-30b) in rat dorsal root ganglia (DRG) contributes to chemotherapy-induced neuropathic pain by regulating the Nav1.
View Article and Find Full Text PDFGut Microbiome and Serum Metabolites in Neuropathic Pain: The PPARα Perspective.
Behav Brain Res
January 2025
Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin 300052, China; Tianjin Research Institute of Anesthesiology, Tianjin 300052, China. Electronic address:
Neuropathic pain (NP) is a chronic disease state centred on neuroinflammation with a high prevalence and limited effective treatment options. Peroxisome proliferator-activated receptor α (PPARα) has emerged as a promising target for NP management due to its anti-inflammatory properties. Recent evidence highlights the critical role of the gut microbiome and its metabolites in NP pathogenesis.
View Article and Find Full Text PDFEvaluation of an indirect Na1.7 inhibitor as adjunctive analgesic in burn-related neuropathic pain in a cat.
Vet Anaesth Analg
January 2025
Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, FL, USA.
Burn-related neuropathic pain (BRNP) can arise following burn-induced nerve damage, affects approximately 6% of burned human patients and can result in chronic pain. Although widely studied in humans, data on BRNP or its treatment in animals is lacking. A 4-year-old domestic shorthair cat was presented with an infected, non-healing wound suspected to be a caustic burn.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!