Use of dietary supplements is widespread, yet intakes from supplements are difficult to quantify. The Supplement Reporting study utilized a unique inventory method to quantify dietary supplement use across 1 year in a sample of 397 supplement users. Interviewers visited participants' homes in 2005-2006 to record supplement purchases and the number of pills in each supplement bottle every 3 months. Total use for the year was calculated from these inventories. Participants in this observational study were older adults (average age 68 years) from the Multiethnic Cohort in Hawaii and Los Angeles, CA, with approximately equal representation of men and women and six ethnic groups (white, Japanese American, Hawaiian, African American, Latinos born in the United States, and Latinos born elsewhere). The most commonly used supplement type was one-a-day multivitamins/minerals, which were taken at least once during the year by 83% of men and 73% of women. Other common supplements were vitamin C, fish oil, vitamin E, and bone or joint supplements. Participants used a median of seven (women) and five and a half (men) different supplements during the year. There were few differences in supplement use across ethnic groups for men, but use tended to be highest for white and Japanese-American women. Use of nonvitamin/nonmineral supplements was common among these older adults, sometimes at high doses. When assessing intakes, supplement use should be correctly quantified because users tend to take many different supplements and nutrient intakes from supplements can be substantial. The inventory method may help improve the measurement of supplement use.
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http://dx.doi.org/10.1016/j.jada.2011.04.004 | DOI Listing |
Alzheimers Dement
December 2024
Brunel University London, London, United Kingdom.
Background: Psychosis occurs in 30-40% of individuals with AD. New insights into disease mechanisms may lead to novel pharmacological targets and treatments. Previous studies have focused on bulk tissue analysis with limited results.
View Article and Find Full Text PDFEur J Epidemiol
January 2025
Department of Epidemiology and Health Monitoring, Robert Koch Institute, Gerichtstr. 27, D-13347, Berlin, Germany.
An association of mental health and in particular depression with cardiovascular disease has been shown in adults and to a lesser extent in the young. Recently improved measurement methods of carotid-intima media thickness (CIMT) and carotid stiffness (CS) allow more differentiated analyses of this link. We examined 4,361 participants of the nationwide KiGGS cohort aged 3-17 years at baseline and 14-28 years at follow-up.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
The Cyprus Institute, Climate and Atmosphere Research Center, 2121, Nicosia, Cyprus.
The production of nitrogen oxides (NO = NO + NO ) is substantial in urban areas and from fossil fuel-fired power plants, causing both local and regional pollution, with severe consequences for human health. To estimate their emissions and implement air quality policies, authorities often rely on reported emission inventories. The island of Cyprus is de facto divided into two different political entities, and as a result, such emissions inventories are not systematically available for the whole island.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Dublin, Dublin 2, Ireland.
Background: Amyotrophic lateral sclerosis (ALS) shares pathological and genetic underpinnings with frontotemporal dementia (FTD). ALS manifests with diverse symptoms, including progressive neuro-motor degeneration, muscle weakness, but also cognitive-behavioural changes in up to half of the cases. Resting-state EEG measures, particularly spectral power and functional connectivity, have been instrumental for discerning abnormal motor and cognitive network function in ALS [1]-[3].
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California San Diego, La Jolla, CA, USA.
Background: In people with Lewy body (LB) pathology, Alzheimer's (AD) co-pathology staging has stronger association with cognition for females, and LB pathology staging has stronger association with behavioral and motor symptoms for males. As APOEe4 allele is a risk factor for LB and AD pathologies, in both females and males; we investigated whether APOEe4 association with clinical profile and pathology staging differs by sex in people with LB pathology.
Methods: Data were obtained from the National Alzheimer's Coordinating Center Uniform Data Set (UDS), Neuropathology and Genetic Data Set for UDS visits conducted between September 2005 and August 2019.
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