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| http://dx.doi.org/10.1038/jid.2011.181 | DOI Listing |
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Systematic identification of pathogenic variants of non-small cell lung cancer in the promoters of DNA-damage repair genes.
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Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China; Research Units of Cohort Study on Cardiovascular Diseases and Cancers, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address:
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- Deficiency in DNA-damage repair (DDR) genes is linked to a higher risk of lung cancer, especially due to rare loss-of-function variants, prompting research into the role of rare regulatory variants.* -
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