Objectives: To evaluate the association between urinary pH and metabolic risk factors, including obesity according to sex in a Korean population recruited through the health promotion center.
Methods: From 2008 to 2010, a total of 22 297 ostensibly healthy adult Koreans who visited our health promotion center were enrolled in the present study. The relationship between urinary pH and various metabolic risk factors, including obesity, were evaluated.
Results: The mean age ± SD of the study population was 45.0 ± 9.1 years. The men had a significantly greater body mass index and lower urinary pH than the women. Using multivariate logistic regression analysis, obesity significantly correlated with a lower urinary pH (≤5.5) only in men (odds ratio [OR] 1.095, P = .015) and not in women (OR 1.004, P = 0.945). Among the various factors examined, older age (>45 years), greater fasting blood glucose, and hyperuricemia were factors significantly associated with a lower urinary pH in both groups. Hypertriglyceridemia was a significant factor associated with lower urinary pH only in men, and a lower high-density lipoprotein cholesterol was the significant factor for a lower urinary pH in women.
Conclusions: The results of the present study revealed that obesity is significantly correlated with lower urinary pH (≤5.5) only in men.
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http://dx.doi.org/10.1016/j.urology.2011.04.033 | DOI Listing |
Neurourol Urodyn
December 2024
Department of Physical Medicine and Rehabilitation, Rothschild Hospital, Sorbonne Université, Paris, France.
Context: Lower Urinary Tract Symptoms (LUTS) are defined by their distressing effect on patients' day-to-day life. Given the pressures on secondary care resources, LUTS may be overlooked or inadequately assessed and therefore patients may be burdened for an extended period before treatment.
Methods: In a debate held at the International Consultation on Incontinence Research Society (ICI-RS) meeting in Bristol in June 2024, we considered how new technologies might contribute to an expedited, dignified and effective investigation of LUTS.
Purpose: To evaluate the safety and efficacy of sublingual methazolamide in patients with open-angle glaucoma (OAG) and inform future trial design.
Methods: Fourteen participants (28 eyes) aged 50 to 90 years with bilateral OAG and intraocular pressure (IOP) between 18 and 35 mmHg after medication washout were included. Participants were randomized to receive either 25 mg or 50 mg of sublingual methazolamide once daily for one week, followed by twice-daily administration during the second week.
J Surg Case Rep
January 2025
Department of Urology, North Middlesex University Hospital, Sterling Way, London N18 1QX, United Kingdom.
Genitourinary tuberculosis is the second most common form of extrapulmonary tuberculosis. We present the case of a male patient in his late 20s who presented to his general practitioner with symptoms of recurrent urinary tract infection (UTI). Upon investigation his estimated glomerular filtration rate was found to be 61 ml/min/1.
View Article and Find Full Text PDFCancer Sci
December 2024
Cixi Institute of Biomedical Engineering, Chinese Academy of Science (CAS), Ningbo Institute of Materials Technology and Engineering, CAS Ningbo, Ningbo, China.
Urothelial carcinoma (UC) can arise from either the lower urinary tract or the upper tract; they represent different disease entities and require different clinical treatment strategies. A full understanding of the cellular characteristics in UC may guide the development of novel therapies. Here, we performed single-cell transcriptome analysis from four patients with UC of the bladder (UCB), five patients with UC of the ureter (UCU), and four patients with UC of the renal pelvis (UCRP) to develop a comprehensive cell atlas of UC.
View Article and Find Full Text PDFVirulence
December 2025
Department of Infectious Diseases, Univ Rouen Normandie, Université de Caen Normandie, INSERM, Normandie Univ, DYNAMICURE UMR 1311, CHU Rouen, Rouen, France.
Specific determinants associated with Uropathogenic (UPEC) causing recurrent cystitis are still poorly characterized. Using strains from a previous clinical study (Vitale study, clinicaltrials.gov, identifier NCT02292160) the aims of this study were (i) to describe genomic and phenotypic traits associated with recurrence using a large collection of recurrent and paired sporadic UPEC isolates and (ii) to explore within-host genomic adaptation associated with recurrence using series of 2 to 5 sequential UPEC isolates.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!