Little is known about factors differentiating more and less effective therapists or the mechanisms through which therapists influence outcome. In the present study, the performance of a small sample of 4 therapists was compared in the context of delivering cognitive-behavioral psychotherapy (CBT) to 32 clients with generalized anxiety disorder. More effective therapists were characterized by higher observer-rated CBT competence, higher client outcome expectations and client treatment credibility assessments, and higher early treatment client ratings of therapeutic alliance quality. Higher early CBT competence was associated with higher client midtreatment outcome expectations, which in turn were associated with better posttreatment outcomes. Although these findings are preliminary given the small sample of therapists and clients, they suggest that the common factor of outcome expectations might be a mechanism through which the specific factor of psychotherapist competence exerts its influence on treatment outcome. The implications of these findings and directions for future research are discussed.
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http://dx.doi.org/10.1037/a0022011 | DOI Listing |
Braz J Psychiatry
January 2025
Department of Preventive Medicine, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Objective: This study aims to evaluate if attitudes toward drug use, decision-making, communication, and alcohol resistance skills act as predictors of alcohol use and binge drinking initiation among Brazilian students, considering the sex differences.
Methods: We used a longitudinal sample of 1,103 seventh-grade students from 15 Brazilian public schools. We explored if attitudes toward drug use, decision-making, communication, and alcohol resistance skills at baseline predicted alcohol outcomes nine months later.
Cardiol Rev
January 2025
Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan.
Obstructive sleep apnea (OSA), a highly prevalent and serious disorder with significant complications, causes considerable daytime and nighttime symptoms as well as long-term consequences and is yet an underdiagnosed and inadequately treated condition. Patients with OSA undergo frequent awakenings during the sleep cycle and find it impossible to get restorative sleep. Individuals are extremely fatigued, sleepy, and irritable throughout the day.
View Article and Find Full Text PDFDisabil Rehabil
January 2025
CanChild Center for Childhood-Onset Disability Research, McMaster University, Hamilton, Canada.
Purpose: This study explores the experiences of autistic youth and neurodivergent job coaches during a job training program.
Methods: Interpretive Description methodology guided this study. Two researchers facilitated virtual focus groups with autistic students and neurodivergent job coaches separately before (n = 14) and after (n = 12) the program.
Clin Transl Sci
January 2025
Pharmacometrica, La Fouillade, France.
Placebo effect represents a serious confounder for the assessment of treatment effect to the extent that it has become increasingly difficult to develop antidepressant medications appropriate for outperforming placebo. Treatment effect in randomized, placebo-controlled trials, is usually estimated by the mean baseline adjusted difference of treatment response in active and placebo arms and is function of treatment-specific and non-specific effects. The non-specific treatment effect varies subject by subject conditional to the individual propensity to respond to placebo.
View Article and Find Full Text PDFAlzheimers Dement
January 2025
Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology, Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Introduction: Transcranial pulse stimulation (TPS) is increasingly being investigated as a promising potential treatment for Alzheimer's disease (AD). Although the safety and preliminary clinical efficacy of TPS short pulses have been supported by neuropsychological scores in treated AD patients, its fundamental mechanisms are uncharted.
Methods: Herein, we used a multi-modal preclinical imaging platform combining real-time volumetric optoacoustic tomography, contrast-enhanced magnetic resonance imaging, and ex vivo immunofluorescence to comprehensively analyze structural and hemodynamic effects induced by TPS.
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