The Article highlights the fact that without a homogeneous definition of acute renal injuries of adults and infants, for the last 5 years a new classification system has appeared. The RIFLE pediatric criteria are looked over, validated in 2007 which allow a better IRA classification at infants and allow comparisons between the intensive care units and also allow assumptions on the predictions of the disease. The list of certain causes of IRA at infants is rendered, the genetic background of children with IRA risk is highlighted, the necessity of reevaluating and criteria of evaluating renal functions is underlined. The etiology of renal failure was studied on 110 infants interned on a period of 5 years (2003- 2008) in 2 centers with different profile: The Clinic Of Pediatric Nephrology "Sf. Maria" Iaşi and the Intensive Care Compartment of The Pediatric Hospital "Sf. Ioan" Galaţi.
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