The importance of methylmalonic acid dosage on the assessment of patients with neurological manifestations following bariatric surgery.

Obes Surg

Clinic of Neuromuscular Diseases, DINEP-Neurology and Epidemiology Division, University Complex Professor Edgar Santos, Federal University of Bahia, Salvador, Bahia, Brazil.

Published: December 2011

Vitamin B12 or cyanocobalamin is an important substance that is included in several metabolic pathways. Its deficiency is a common event after bariatric surgery, decreasing the vitamin B12 absorption after almost all of the stomach and duodenum are eliminated from the digestion process. Neurological manifestations of cyanocobalamin deficiency are not uncommon. We report a case of a young woman who developed ataxia, weakness and peripheral neuropathy after bariatric surgery, but with normal value of vitamin B12 dosage. For the diagnosis, it was necessary to dose methylmalonic acid. We discuss the importance of methylmalonic acid dosage after bariatric surgery in patients who present suspect of cyanocobalamin deficiency with normal values of this vitamin and the role of proton pump inhibitor use and vitamin supplementation in patients with early neurological presentation.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11695-011-0449-3DOI Listing

Publication Analysis

Top Keywords

bariatric surgery
16
methylmalonic acid
12
vitamin b12
12
acid dosage
8
neurological manifestations
8
cyanocobalamin deficiency
8
vitamin
5
dosage assessment
4
assessment patients
4
patients neurological
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!