Surface immobilizable chelator for label-free electrical detection of pyrophosphate.

Chem Commun (Camb)

Integrated Biosystems Lab, Intel Labs, Intel Corporation, 2200 Mission College Blvd., Santa Clara, CA 95054, USA.

Published: August 2011

A new pyrophosphate (PPi) chelator was designed for surface-sensitive electrical detection of biomolecular reactions. This article describes the synthesis of the PPi-selective receptor, its surface immobilization and application to label-free electrical detection on a silicon-based field-effect transistor (FET) sensor.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361515PMC
http://dx.doi.org/10.1039/c1cc12073eDOI Listing

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