Kilowatt-peak-power, single-frequency, pulsed fiber laser near 2 μm.

Opt Lett

AdValue Photonics, 3708 East Columbia Street, Suite 100, Tucson, Arizona 85714, USA.

Published: June 2011

AI Article Synopsis

  • Generated single-frequency pulses at kilowatt peak power from an all-fiber Tm-doped system, marking a first in the 2 μm laser region.
  • Observed spectral broadening by a factor of 3 in the amplified pulses due to self-phase modulation in accompanying passive fibers.
  • Short pulse width of ~7 ns prevents stimulated Brillouin scattering, enabling significant nonlinear spectral broadening in single-mode fiber, which aids in generating mid- and long-wavelength infrared supercontinuum.

Article Abstract

We generated single-frequency pulses at kilowatt peak power from an all-fiber Tm-doped master oscillator power amplifier system, which is the first report of this kind (to the best of our knowledge) of a laser in the 2 μm region. Compared with the laser linewidth of seed pulses, spectral broadening by a factor of 3 was observed with the amplified pulses. This was attributed to self-phase modulation in passive pigtail fibers of the components (isolator and wavelength division multiplexing) that were placed after the fiber amplifier. The short pulse width (~7 ns) of the kilowatt-level pulses prevents an onset of stimulated Brillouin scattering in the long fiber. When launching the pulses into several-meter single-mode fiber, significant nonlinear spectral broadening occurs due to modulation instability in the fiber. This reaction is beneficial for generation of a mid- and long-wavelength IR supercontinuum in nonlinear IR fibers.

Download full-text PDF

Source
http://dx.doi.org/10.1364/OL.36.002293DOI Listing

Publication Analysis

Top Keywords

laser μm
8
spectral broadening
8
fiber
5
pulses
5
kilowatt-peak-power single-frequency
4
single-frequency pulsed
4
pulsed fiber
4
fiber laser
4
μm generated
4
generated single-frequency
4

Similar Publications

Thermo-responsive gold nanorod vesicles for combined NIR-II photothermal therapy and chemotherapy of solid tumors.

Acta Biomater

January 2025

State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address:

Photothermal therapy (PTT) is a promising treatment strategy for malignant tumors. Photothermal agents which can achieve efficient photothermal conversion in the NIR-II region plays crucial roles in this remedy. Here, we report one type of thermo-responsive gold nanorod vesicles USGRV-17-AAG for combined NIR-II photothermal therapy and chemotherapy of solid tumors.

View Article and Find Full Text PDF

An Orbitrap/Time-of-Flight Mass Spectrometer for Photofragment Ion Imaging and High-Resolution Mass Analysis of Native Macromolecular Assemblies.

J Am Soc Mass Spectrom

July 2023

Maastricht MultiModal Molecular Imaging (M4i) Institute, Division of Imaging Mass Spectrometry (IMS), Maastricht University, 6229 ER Maastricht, The Netherlands.

We discuss the design, development, and evaluation of an Orbitrap/time-of-flight (TOF) mass spectrometry (MS)-based instrument with integrated UV photodissociation (UVPD) and time/mass-to-charge ratio (/)-resolved imaging for the comprehensive study of the higher-order molecular structure of macromolecular assemblies (MMAs). A bespoke TOF analyzer has been coupled to the higher-energy collisional dissociation cell of an ultrahigh mass range hybrid quadrupole-Orbitrap MS. A 193 nm excimer laser was employed to photofragment MMA ions.

View Article and Find Full Text PDF

Monitoring of extracellular matrix (ECM) microstructure is essential in studying structure-associated cellular processes, improving cellular function, and for ensuring sufficient mechanical integrity in engineered tissues. This paper describes a novel method to study the microscale alignment of the matrix in engineered tissue scaffolds (ETS) that are usually composed of a variety of biomacromolecules derived by cells. First, a trained loading function was derived from Raman spectra of highly aligned native tissue via principal component analysis (PCA), where prominent changes associated with specific Raman bands (e.

View Article and Find Full Text PDF

Engineering near-infrared laser-activated gold nanorod vesicles with upper critical solution temperature for photothermal therapy and chemotherapy.

J Colloid Interface Sci

June 2023

State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address:

Article Synopsis
  • - Researchers have developed a new type of gold nanorod drug delivery system (UGRV-DOX) that enhances cancer treatment through multimodal synergistic therapy and utilizes the unique properties of gold nanorods for photothermal therapy.
  • - The UGRV-DOX vesicles are designed with a hollow structure to increase drug loading capacity and are made with specialized polymers that minimize drug leakage, allowing for effective and controlled drug release when exposed to light.
  • - In animal studies, these nanovesicles demonstrated a powerful anti-tumor effect, significantly reducing tumor size by 99.3% when treated with an 808 nm laser, showcasing their potential for precise cancer treatment.
View Article and Find Full Text PDF

Enhanced Spatial Mapping of Histone Proteoforms in Human Kidney Through MALDI-MSI by High-Field UHMR-Orbitrap Detection.

Anal Chem

September 2022

Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, United States.

Core histones including H2A, H2B, H3, and H4 are key modulators of cellular repair, transcription, and replication within eukaryotic cells, playing vital roles in the pathogenesis of disease and cellular responses to environmental stimuli. Traditional mass spectrometry (MS)-based bottom-up and top-down proteomics allows for the comprehensive identification of proteins and of post-translational modification (PTM) harboring proteoforms. However, these methodologies have difficulties preserving near-cellular spatial distributions because they typically require laser capture microdissection (LCM) and advanced sample preparation techniques.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!