Objectives: We compared nitrite, B-type natriuretic peptide (BNP), and cGMP levels in preeclamptic with those found in healthy pregnant.
Methods: We studied 21 healthy pregnant and 27 preeclamptic. Plasma cGMP and BNP levels were determined by ELISA. Nitrite levels were determined by chemiluminescence.
Results: Higher cGMP and BNP, and lower nitrite levels were found in preeclamptic versus healthy pregnant.
Conclusions: Altered cGMP levels reflect increased BNP levels and not impaired nitric oxide activity in preeclampsia.
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http://dx.doi.org/10.1016/j.clinbiochem.2011.05.026 | DOI Listing |
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