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Complex odontoma is a benign odontogenic tumor composed of disorganized dental tissues, including enamel, dentin, cementum, and pulp. Unlike compound odontomas, which exhibit tooth-like structures, complex odontomas form a mass without anatomical organization. These tumors frequently present without symptoms and are typically identified inadvertently during standard dental imaging procedures.

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Article Synopsis
  • Primordial odontogenic tumor (POT) is a rare benign tumor commonly found in children and young adults, often presenting as asymptomatic swelling, particularly in the posterior mandible.
  • A systematic review of 26 studies, covering 36 POT cases, analyzed various clinical characteristics, treatments, and outcomes, revealing a median patient age of 12 years and a slight male predominance.
  • Most POTs exhibited unilocular radiolucencies on imaging and were primarily treated through enucleation and curettage, with one recurrence noted among cases with follow-up data.
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The term "unicystic ameloblastoma" describes cystic lesions that exhibit radiographic, clinical, or gross characteristics of a jaw cyst. However, histologic examination reveals a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less prevalent kind of ameloblastoma.

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Surrogate Immunohistochemical Markers of Proliferation and Embryonic Stem Cells in Distinguishing Ameloblastoma from Ameloblastic Carcinoma.

Head Neck Pathol

October 2024

Department of Oral and Maxillofacial Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria Oral Health Care Centre, Office 6-11, Corner of Steve Biko and Dr Savage Roads, Pretoria, 0084, South Africa.

Purpose: The current study aimed to investigate the use of surrogate immunohistochemical (IHC) markers of proliferation and stem cells to distinguish ameloblastoma (AB) from ameloblastic carcinoma (AC).

Methods: The study assessed a total of 29 ACs, 6 ABs that transformed into ACs, and a control cohort of 20 ABs. The demographics and clinicopathologic details of the included cases of AC were recorded.

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Article Synopsis
  • Delayed eruption of permanent teeth is common, but impaction of the mandibular first molar is rare, often caused by issues like odontogenic cysts and tumors.
  • The article details two cases where odontogenic tumors led to the delayed eruption of the mandibular first molar in children, with specific diagnoses of ameloblastic fibro-odontoma and odontoma.
  • Treatment involved curettage of the tumors and fenestration of the impacted molars, which resulted in the successful eruption of the first molar in both cases.
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