There are many explanations for high rates of sexual aggression, with no one theory dominating the field. This study extends past research by evaluating an expanded version of the confluence model with a community sample. One-hour audio computer-assisted self-interviews were completed by 470 young single men. Using structural equation analyses, delinquency, hostile masculinity, impersonal sex, and misperception of women's sexual cues were positively and directly associated with the number of sexually aggressive acts committed. There were also indirect effects of childhood victimization, personality traits associated with subclinical levels of psychopathy, and alcohol consumption. These findings demonstrate the usefulness of the confluence model, as well as the importance of broadening this theory to include additional constructs.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139770 | PMC |
http://dx.doi.org/10.1002/ab.20399 | DOI Listing |
ACS Pharmacol Transl Sci
January 2025
Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, United States Food and Drug Administration (FDA), Silver Spring, Maryland 20993, United States.
Current in vitro cell-based methods, relying on single cell types, have structural and functional limitations in determining lung drug permeability, which is a contributing factor affecting both local and systemic drug levels. To address this issue, we investigated a 3D human lung airway model generated using a cell culture insert, wherein primary human lung epithelial and endothelial cells were cocultured at an air-liquid interface (ALI). To ensure that the cell culture mimics the physiological and functional characteristics of airway tissue, the model was characterized by evaluating several parameters such as cellular confluency, ciliation, tight junctions, mucus-layer formation, transepithelial electrical resistance, and barrier function through assaying fluorescein isothiocyanate-dextran permeability.
View Article and Find Full Text PDFBlack Americans (AA) face a confluence of challenges when seeking care including unaffordable costs, negative experiences with providers, racism, and distrust in the healthcare system. This study utilized linear regressions and mediation analysis to explore the interconnectedness of these challenges within a community-based sample of 313 AA women aged 45 and older. Approximately 23% of participants reported affordability problems, while 44% had a negative experience with a provider.
View Article and Find Full Text PDFMol Biol Rep
January 2025
Goat Genetics and Breeding Division, ICAR-Central Institute for Research On Goats, Makhdoom, Farah, Mathura, 281 122, Uttar Pradesh, India.
Background: Extracellular matrix (ECM) proteins play a crucial role in regulating the biological properties of adherent cells. For cryopreserved fibroblasts, a favourable ECM environment can help restore their natural morphology and function more rapidly, minimizing post-thaw stress responses.
Methods And Results: This study explored the functional responses of cryopreserved enriched caprine adult dermal fibroblast (cadFibroblast) cells to structural [collagen-IV and rat tail collagen (RTC)] and adhesion ECM proteins (laminin, fibronectin, and vitronectin) under in vitro culture conditions.
Int J Mol Sci
December 2024
Laboratory of Animal Biology, National Institute for Research and Development for Biology and Animal Nutrition, Calea Bucuresti No. 1, Balotesti, 077015 Ilfov, Romania.
The present study aimed to investigate the ability of an aqueous extract derived from mustard seed meal to counteract the effects of endotoxin lipopolysaccharide (LPS) on the intestinal epithelium. Caco-2 cells were cultured together with HT29-MTX and used as a cellular model to analyze critical intestinal parameters, such as renewal, integrity, innate immunity, and signaling pathway. Byproducts of mustard seed oil extraction are rich in soluble polysaccharides, proteins, allyl isothiocyanates, and phenolic acids, which are known as powerful antioxidants with antimicrobial and antifungal properties.
View Article and Find Full Text PDFJ Environ Radioact
January 2025
Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PSE-ENV/STAAR/LRTA, PSE-ENV/SPDR/LT2S, Saint-Paul-lez-Durance, F-13115, France. Electronic address:
The transfer of radionuclides discharged into rivers by nuclear facilities are conditioned by their solid/liquid fractionation, commonly represented by an equilibrium approach using the distribution coefficient K. This coefficient, largely used in modeling, assumes an instantaneous and completely reversible reaction. However, such assumptions are rarely verified.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!