Investigation of self-immolative linkers in the design of hydrogen peroxide activated metalloprotein inhibitors.

Chem Commun (Camb)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, USA.

Published: July 2011

A series of self-immolative boronic ester protected methyl salicylates and metal-binding groups with various linking strategies have been investigated for their use in the design of matrix metalloproteinase proinhibitors.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682828PMC
http://dx.doi.org/10.1039/c1cc12526eDOI Listing

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