In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147744PMC
http://dx.doi.org/10.1128/JCM.01102-11DOI Listing

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