Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.
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| http://dx.doi.org/10.1039/c1cc12236c | DOI Listing |
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