AI Article Synopsis
- GISTs are tumors that usually develop in the gastrointestinal tract, but cases from the pancreas are extremely rare; this report focuses on a unique instance.
- A 74-year-old woman had an abdominal mass confirmed as a GIST after a biopsy, and she underwent surgery to remove part of her pancreas.
- This case is notable as the first of its kind to show a patient surviving over five years after surgery for a GIST originating from the pancreas without any recurrence.
Article Abstract
Background: Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term follow-up of the patients.
Method: This report describes an interesting and unusual case of GIST arising from the pancreas.
Results: A 74-year-old female presented with a palpable abdominal mass. CT scan showed a large mass 11 x 8 x 4 cm originating from the tail of the pancreas. Percutaneous biopsy revealed a GIST predominantly with spindle cells, but some parts also contained epitheloid cells. The patient was treated by distal pancreatic resection with splenectomy. Immunohistochemistry of the tumor showed a staining pattern characteristic of GIST. The patient has achieved a long-term survival of five years and six months without any sign of recurrence of the disease.
Conclusion: This is the first reported case of an extra-gastrointestinal stromal tumor arising from the pancreas treated surgically, with a long-term survival.
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| http://dx.doi.org/10.1016/s1499-3872(11)60056-8 | DOI Listing |
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